感染寄生虫的豚鼠小肠上皮的类过敏反应。
Anaphylactic-like reaction of small intestinal epithelium in parasitized guinea-pigs.
作者信息
Russell D A, Castro G A
出版信息
Immunology. 1985 Mar;54(3):573-9.
Abstract
Antigens derived from Trichinella spiralis were used to challenge, in vitro, sensitized jejunum from infected guinea-pigs while monitoring ion transport properties of the tissue. Antigen challenge resulted in dose-dependent increases in trans-epithelial electrical potential difference and short circuit current. Both antigen-stimulated electrical alterations and Schultz-Dale contractions were demonstrated in small intestinal tissue after the passive transfer of immune serum containing anti-trichinella homocytotropic antibodies.
摘要
来自旋毛虫的抗原被用于在体外刺激受感染豚鼠的致敏空肠，同时监测该组织的离子转运特性。抗原刺激导致跨上皮电势差和短路电流呈剂量依赖性增加。在被动转移含有抗旋毛虫亲同种细胞抗体的免疫血清后，小肠组织中出现了抗原刺激的电变化和舒尔茨 - 戴尔收缩反应。
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