Wei Ning, Wang Xinxin, Lyu Mengyu, Chen Ling
Department of Rehabilitation Sciences, College of Medicine and Health Science, Wuhan Polytechnic University, Wuhan, Hubei, China.
Department of Nursing, The Second Affiliated Hospital of Zhejiang University School of Medicine, Hangzhou, Zhejiang, China.
BMC Public Health. 2024 Dec 26;24(1):3592. doi: 10.1186/s12889-024-21178-1.
The association between sleep quality and depressive symptoms was established, which could be varied by some mediators. Muscle strength might be a potential mediator for this association. The purpose of this study was to explore the mediating role of muscle strength in the relationship between sleep quality and depressive symptoms among the older individuals with or without dynapenia.
Three hundreds and nine older adults were allocated into two groups: dynapenia and non-dynapenia groups. The handgrip strength was assessed by the hand-held dynamometer. The quality of sleep and depressive symptoms were evaluated using Pittsburgh Sleep Quality Index and the 15-item Geriatric Depression Scale, respectively. The ProcessV3.3 was used to estimate the simple mediation model, with controlled covariates and centralized variables.
In both dynapenia (n = 142) and non-dynapenia (n = 167) groups, the quality of sleep was positively correlated to depressive symptoms, while negatively related to muscle strength (p < 0.05). Meanwhile, depressive symptoms were negatively correlated to muscle strength (dynapenia: p = 0.001; non-dynapenia: p < 0.001). Muscle strength only acted as a mediator accounting for 10.04% of the total effect of sleep quality on depressive symptoms in the older individuals with dynapenia. No mediating role was found in the effect of depressive symptoms on sleep quality in both dynapenia and non-dynapenia group.
Muscle strength was a mediator in the one direction of the relationship between sleep quality and depressive symptoms (the effect of PSQI on GDS-15) in older individuals with dynapenia.
睡眠质量与抑郁症状之间的关联已得到证实，且这种关联可能会因某些中介因素而有所不同。肌肉力量可能是这种关联的一个潜在中介因素。本研究的目的是探讨肌肉力量在有或无肌肉减少症的老年人睡眠质量与抑郁症状之间关系中的中介作用。
309名老年人被分为两组：肌肉减少症组和非肌肉减少症组。使用握力计评估握力。分别使用匹兹堡睡眠质量指数和15项老年抑郁量表评估睡眠质量和抑郁症状。使用ProcessV3.3估计简单中介模型，并对协变量和中心化变量进行控制。
在肌肉减少症组（n = 142）和非肌肉减少症组（n = 167）中，睡眠质量均与抑郁症状呈正相关，而与肌肉力量呈负相关（p < 0.05）。同时，抑郁症状与肌肉力量呈负相关（肌肉减少症组：p = 0.001；非肌肉减少症组：p < 0.001）。在有肌肉减少症的老年人中，肌肉力量仅作为中介因素，占睡眠质量对抑郁症状总效应的10.04%。在肌肉减少症组和非肌肉减少症组中，均未发现抑郁症状对睡眠质量的中介作用。
在有肌肉减少症的老年人中，肌肉力量是睡眠质量与抑郁症状之间单向关系（PSQI对GDS - 15的影响）的中介因素。
