Abid Syed, Jananth Humaira, Chowdhury Sayeda M, Ahmed Tanveer
General Internal Medicine, East and North Hertfordshire NHS Trust, Stevenage, GBR.
Medicine, East and North Hertfordshire NHS Trust, Stevenage, GBR.
Cureus. 2024 Nov 25;16(11):e74461. doi: 10.7759/cureus.74461. eCollection 2024 Nov.
Hypertension remains a significant global health issue, increasingly affecting younger populations due to lifestyle and dietary changes. This case report presents a 28-year-old male diagnosed with primary hyperaldosteronism, a rare but treatable cause of secondary hypertension, presenting as hypertensive urgency. The patient reported persistent headaches and weakness, with an initial blood pressure of 190/120 mmHg and severe hypokalemia. Through a systematic diagnostic approach, including biochemical and imaging assessments, unilateral adrenal hyperplasia was identified as the cause of primary hyperaldosteronism. Targeted treatment, including antihypertensive agents, potassium supplementation, and mineralocorticoid receptor antagonists, led to significant improvements in blood pressure and electrolyte levels. This case underscores the importance of considering secondary hypertension causes in young adults and the potential for positive outcomes with accurate, resource-conscious diagnostic and management strategies.
高血压仍然是一个重大的全球健康问题，由于生活方式和饮食变化，它对年轻人群的影响日益增加。本病例报告介绍了一名28岁男性，被诊断为原发性醛固酮增多症，这是一种导致继发性高血压的罕见但可治疗的病因，表现为高血压急症。患者自述持续头痛和乏力，初始血压为190/120 mmHg，伴有严重低钾血症。通过系统的诊断方法，包括生化和影像学评估，确定单侧肾上腺增生是原发性醛固酮增多症的病因。针对性治疗，包括使用抗高血压药物、补充钾和使用盐皮质激素受体拮抗剂，使血压和电解质水平得到显著改善。本病例强调了在年轻成年人中考虑继发性高血压病因的重要性，以及采用准确、资源节约型诊断和管理策略取得积极结果的可能性。
