Mirimanoff R O, Wang C C, Doppke K P
Int J Radiat Oncol Biol Phys. 1985 Mar;11(3):499-504. doi: 10.1016/0360-3016(85)90180-4.
The survival, pattern of failure and complications in 47 patients with Stage III and IV cancers of the glottis, supraglottis and hypopharynx treated with surgery and postoperative radiotherapy using a new treatment technique referred to as "mini-mantle" were analyzed. The absolute survival probability of the entire group was 53 and 31% at 3 and 5 years. The local control probability at 3 and 5 years was 63 and 58%, and was higher for the supraglottic/hypopharyngeal than for glottic carcinomas. Advanced lesions, lymph node metastases and positive resection margins were significantly related to a worse local control. Five patients developed complications requiring surgical correction, but none experienced mortality. Moderate complications were treated conservatively without lasting sequelae. This technique is a reasonably safe and efficient procedure and can be effectively employed for the management of advanced laryngeal and hypopharyngeal carcinomas after definitive surgery.
对47例声门、声门上区和下咽III期及IV期癌症患者采用一种称为“迷你斗篷”的新治疗技术进行手术及术后放疗后的生存情况、失败模式和并发症进行了分析。整个组在3年和5年时的绝对生存概率分别为53%和31%。3年和5年时的局部控制概率分别为63%和58%，声门上区/下咽癌的局部控制概率高于声门癌。晚期病变、淋巴结转移和切缘阳性与较差的局部控制显著相关。5例患者出现需要手术矫正的并发症，但无一例死亡。中度并发症经保守治疗无持久后遗症。该技术是一种相当安全有效的方法，可有效用于确定性手术后晚期喉癌和下咽癌的治疗。
