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欧盟罕见病组织(EUFOREA)2024年举办的2型炎症欧洲生物制剂培训课程:关键事实与经验教训

European biologic training course for type 2 inflammation by EUFOREA in 2024: key facts and lessons learned.

作者信息

Conti D M, Backer V, Fokkens W, Gevaert P, Peters A, Scadding G K, Pavord I, Lau S, Wechsler M, Bertels X, Liva G, Doulaptsi M, Prokopakis E, Hellings P W

机构信息

Allergy and Clinical Immunology Research Unit, Department of Microbiology and Immunology, KU Leuven, Leuven, Belgium.

Escuela de Doctorado UAM, Centro de Estudios de Posgrado, Universidad Autónoma de Madrid, Calle Francisco Tomás y Valiente, Madrid, Spain.

出版信息

Front Allergy. 2024 Dec 12;5:1517122. doi: 10.3389/falgy.2024.1517122. eCollection 2024.

DOI:10.3389/falgy.2024.1517122
PMID:39726672
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11669716/
Abstract

The European Forum for Research and Education in Allergy and Airways diseases (EUFOREA) organized the first European Biologic Training Course (EBTC) in Brussels on 1st March 2024. The aim of this hybrid EBTC including both face-to-face and web-based participation was to address the educational needs of physicians dealing with asthma and Chronic Rhinosinusitis with Nasal Polyps (CRSwNP) on the clinically relevant aspects of diagnosing and treatment with biologics. EUFOREA is an international non-for-profit organization forming an alliance of all stakeholders dedicated to reducing the prevalence and burden of chronic respiratory diseases through the implementation of optimal patient care via educational, research, and advocacy activities. The inclusive and multidisciplinary approach of EUFOREA was reflected in faculty coming from the paediatric, allergology, pulmonology, and Ear, Nose and Throat (ENT) speciality and from different continents, with more than 250 participants from over 30 countries in the first EBTC. The current report provides a comprehensive overview of key statements made by the faculty of the EBTC 2024, especially focusing on patient selection for a biologic drug, the communication with patients, the onset of biological treatment and the follow-up in routine clinical practice.

摘要

欧洲过敏与气道疾病研究与教育论坛(EUFOREA)于2024年3月1日在布鲁塞尔举办了首届欧洲生物制剂培训课程(EBTC)。这次混合式EBTC包括面对面和网络参与两种形式,其目的是满足处理哮喘和鼻息肉慢性鼻-鼻窦炎(CRSwNP)的医生在生物制剂诊断和治疗的临床相关方面的教育需求。EUFOREA是一个国际非营利组织,它联合了所有利益相关者,致力于通过教育、研究和宣传活动实施最佳患者护理,以降低慢性呼吸道疾病的患病率和负担。EUFOREA包容和多学科的方法体现在其教员来自儿科、过敏科、肺科以及耳鼻喉(ENT)专科,且来自不同的大陆,在首届EBTC中有来自30多个国家的250多名参与者。本报告全面概述了2024年EBTC教员发表的关键声明,尤其侧重于生物制剂药物的患者选择、与患者的沟通、生物治疗的开始以及常规临床实践中的随访。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dce/11669716/65ae6d04d393/falgy-05-1517122-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dce/11669716/65ae6d04d393/falgy-05-1517122-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/4dce/11669716/65ae6d04d393/falgy-05-1517122-g001.jpg

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本文引用的文献

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Nasal polyp syndrome: a patient-centred term for CRSwNP by EUFOREA.鼻息肉综合征:欧洲鼻科学与鼻-鼻窦疾病研究学会提出的以患者为中心的慢性鼻-鼻窦炎伴鼻息肉术语。
Front Allergy. 2024 Mar 20;5:1372919. doi: 10.3389/falgy.2024.1372919. eCollection 2024.
2
Pre-asthma: a useful concept for prevention and disease-modification? A EUFOREA paper. Part 1-allergic asthma.哮喘前期:对预防和疾病改善而言是个有用的概念?一篇欧盟呼吸研究与创新联盟(EUFOREA)的论文。第1部分——过敏性哮喘
Front Allergy. 2024 Jan 30;4:1291185. doi: 10.3389/falgy.2023.1291185. eCollection 2023.
3
EPOS2020/EUFOREA expert opinion on defining disease states and therapeutic goals in CRSwNP.
EPOS2020/EUFOREA 专家意见:慢性鼻窦炎伴鼻息肉患者疾病分型和治疗目标的定义。
Rhinology. 2024 Jun 1;62(3):287-298. doi: 10.4193/Rhin23.415.
4
EUFOREA/EPOS2020 statement on the clinical considerations for chronic rhinosinusitis with nasal polyps care.EUFOREA/EPOS2020 关于慢性鼻-鼻窦炎伴鼻息肉患者护理的临床考量声明。
Allergy. 2024 May;79(5):1123-1133. doi: 10.1111/all.15982. Epub 2023 Dec 18.
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Reduction of daily maintenance inhaled corticosteroids in patients with severe eosinophilic asthma treated with benralizumab (SHAMAL): a randomised, multicentre, open-label, phase 4 study.贝那鲁肽治疗重度嗜酸性粒细胞性哮喘患者的每日维持吸入性皮质类固醇的降低(SHAMAL):一项随机、多中心、开放性、4 期研究。
Lancet. 2024 Jan 20;403(10423):271-281. doi: 10.1016/S0140-6736(23)02284-5. Epub 2023 Dec 7.
6
Parasitic infections related to anti-type 2 immunity monoclonal antibodies: a disproportionality analysis in the food and drug administration's adverse event reporting system (FAERS).与抗2型免疫单克隆抗体相关的寄生虫感染:美国食品药品监督管理局不良事件报告系统(FAERS)中的不成比例分析
Front Pharmacol. 2023 Nov 14;14:1276340. doi: 10.3389/fphar.2023.1276340. eCollection 2023.
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