Vitola Ian, Angulo Carlos, Baptista-Rosas Raul C, Anaya-Esparza Luis Miguel, Escalante-García Zazil Yadel, Villarruel-López Angélica, Silva-Jara Jorge Manuel
Departamento de Ingeniería Química, Universidad de Guadalajara, CUCEI, Blvd. Marcelino García Barragán 1421, Olímpica, Guadalajara 44430, Jalisco, Mexico.
Grupo de Inmunología y Vacunología, Centro de Investigaciones Biológicas del Noroeste, S.C. (CIBNOR), Instituto Politécnico Nacional 195, Playa Palo de Santa Rita Sur, La Paz 23096, Baja California Sur, Mexico.
BioTech (Basel). 2024 Dec 2;13(4):53. doi: 10.3390/biotech13040053.
plants have been widely investigated for their specific compounds with medicinal properties. These bioactive compounds exert preventive and curative effects on non-communicable and infectious diseases. However, extracts have barely been investigated, although they constitute an affordable option to treat human diseases. Nonetheless, antioxidant, antimicrobial, and immunogenicity effects have been associated with extracts. Furthermore, innovative extraction methods in combination with nanoformulations have been proposed to increase desirable compounds' availability, distribution, and conservation, which can be aided by modern computational tools in a transdisciplinary approach. This review aims to describe available extraction and nanoformulation methods for as well as its known antioxidant, antimicrobial, and immunogenic activities. Critical points on the use of extracts in nanoformulations are identified and some prospects are envisaged.
植物因其具有药用特性的特定化合物而受到广泛研究。这些生物活性化合物对非传染性疾病和传染性疾病具有预防和治疗作用。然而,尽管提取物是治疗人类疾病的一种经济实惠的选择,但对其研究却很少。尽管如此,提取物已被证实具有抗氧化、抗菌和免疫原性作用。此外,有人提出将创新的提取方法与纳米制剂相结合,以提高所需化合物的可用性、分布和保存,这可以通过跨学科方法借助现代计算工具来实现。本综述旨在描述现有的提取物提取和纳米制剂方法,以及其已知的抗氧化、抗菌和免疫原性活性。确定了在纳米制剂中使用提取物的关键点,并展望了一些前景。