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剖宫产术后一名既往健康女性发生暴发性侵袭性曲霉病并文献复习

Fulminant Invasive Aspergillosis in a Previously Healthy Woman After Cesarean Section and a Review of the Literature.

作者信息

Pipitò Luca, Baldino Gennaro, Bartoloni Giovanni, Sanguinetti Maurizio, Ventura Spagnolo Elvira, Cascio Antonio

机构信息

Department of Health Promotion, Mother and Child Care, Internal Medicine and Medical Specialties G D'Alessandro, University of Palermo, 90133 Palermo, Italy.

Infectious and Tropical Diseases Unit, Sicilian Regional Reference Center for the Fight Against AIDS, AOU Policlinico P. Giaccone, 90127 Palermo, Italy.

出版信息

Infect Dis Rep. 2024 Dec 20;16(6):1263-1273. doi: 10.3390/idr16060100.

Abstract

Invasive aspergillosis is an extremely rare condition in healthy and immunocompetent individuals, and very few cases have been reported in previously healthy, pregnant, or postpartum women. We describe a case of invasive aspergillosis in a puerperal patient and present literature review results. We present a case of fulminant invasive pulmonary aspergillosis with cerebral, cardiac, and gastric involvement in a young woman, occurring a few days after an elective cesarean section. The patient succumbed after intensive care unit admission, and the diagnosis was made postmortem through autopsy. A total of 20 cases of invasive aspergillosis have been previously reported in pregnant or postpartum women, with high mortality. The risk of opportunistic fungal infections during pregnancy and postpartum should not be underestimated.

摘要

侵袭性曲霉病在健康和免疫功能正常的个体中极为罕见,此前健康、怀孕或产后的女性中报告的病例极少。我们描述了一例产褥期患者的侵袭性曲霉病病例,并呈现文献综述结果。我们报告了一例年轻女性在择期剖宫产术后数天发生的暴发性侵袭性肺曲霉病,累及脑、心脏和胃。患者入住重症监护病房后死亡,死后经尸检确诊。此前共报告了20例怀孕或产后女性的侵袭性曲霉病病例,死亡率很高。孕期和产后机会性真菌感染的风险不应被低估。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/66dc/11675344/4e0079216d33/idr-16-00100-g001.jpg

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