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脑动脉瘤和动静脉畸形:近红外荧光成像应用于内镜检查的初步经验

Cerebral Aneurysms and Arteriovenous Malformation: Preliminary Experience with the Use of Near-Infrared Fluorescence Imaging Applied to Endoscopy.

作者信息

Aiudi Denis, Iacoangeli Alessio, Mattioli Andrea, Raggi Alessio, Dobran Mauro, Polonara Gabriele, Gigli Riccardo, Iacoangeli Maurizio, Gladi Maurizio

机构信息

Department of Neurosurgery, Marche Polytechnic University, 60126 Ancona, Italy.

Department of Neuroradiology, Marche Polytechnic University, 60126 Ancona, Italy.

出版信息

J Pers Med. 2024 Nov 22;14(12):1117. doi: 10.3390/jpm14121117.

Abstract

Indocyanine green video angiography, integrated into the operative microscope, is frequently used in cerebrovascular surgery. This technology is often preferred, for cost or availability, to Doppler or intraoperative DSA (digital subtraction angiography). With the same assumption it was possible, in our preliminary experience, to partially vicariate the aforementioned devices using the SPY mode of the Stryker endoscope; it allowed the visualization of fluorescence in high definition. A retrospective analysis was conducted on a series of five patients suffering from cerebral aneurysm or AVM (arteriovenous malformation) who underwent, during the last year, surgical treatment with the aid of the microscope supported by the Stryker endoscope in the SPY mode for the visualization of the fluorescence emitted by indocyanine green. All aneurysms were completely excluded from the cerebrovascular circulation in the absence of residues in the collar and occlusion of adjacent vessels; the complete removal of the nidus in all the AVMs was achieved with no residues. The intraoperative use of indocyanine green was a safe, rapid, and effective technique within a preliminary case study of "regular-not giant" aneurysms and superficially located AVM. The endoscopic technique in the SPY mode has allowed to partially vicariate the use of Doppler, intraoperative angiography, and integrated microscope video angiography. For these purposes, we propose, in selected cases, the support of the endoscope in the SPY mode during the microsurgical procedure in order to visualize the green fluorescence of indocyanine.

摘要

整合到手术显微镜中的吲哚菁绿视频血管造影术在脑血管手术中经常使用。由于成本或可用性等原因,这项技术通常比多普勒或术中数字减影血管造影(DSA)更受青睐。基于同样的设想,根据我们的初步经验,使用史赛克内窥镜的SPY模式有可能部分替代上述设备;它能实现高清晰度的荧光可视化。我们对一系列五例患有脑动脉瘤或动静脉畸形(AVM)的患者进行了回顾性分析,这些患者在去年接受了手术治疗,手术借助在SPY模式下的史赛克内窥镜辅助显微镜来观察吲哚菁绿发出的荧光。所有动脉瘤均从脑血管循环中完全排除,瘤颈无残留且相邻血管无闭塞;所有动静脉畸形的病灶均被完全切除,无残留。在“常规而非巨大”动脉瘤和浅表性动静脉畸形的初步病例研究中,术中使用吲哚菁绿是一种安全、快速且有效的技术。SPY模式下的内窥镜技术已能够部分替代多普勒、术中血管造影和整合显微镜视频血管造影的使用。出于这些目的,我们建议在特定病例中,在显微手术过程中采用SPY模式的内窥镜辅助,以观察吲哚菁绿的绿色荧光。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/559f/11678535/44ba1be4c990/jpm-14-01117-g002.jpg

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