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是胎盘植入还是非胎盘植入?胎盘植入谱系疾病的超声评估及一种新的诊断和预后评分系统的临床验证

PAS or Not PAS? The Sonographic Assessment of Placenta Accreta Spectrum Disorders and the Clinical Validation of a New Diagnostic and Prognostic Scoring System.

作者信息

Vimercati Antonella, Galante Arianna, Fanelli Margherita, Cirignaco Francesca, Vitagliano Amerigo, Nicolì Pierpaolo, Tinelli Andrea, Malvasi Antonio, Dellino Miriam, Damiani Gianluca Raffaello, Crescenza Barbara, Baldini Giorgio Maria, Cicinelli Ettore, Cerbone Marco

机构信息

Obstetrics and Gynaecology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari, 70124 Bari, Italy.

Chair of Medical Statistic, Department of Interdisciplinary Medicine (DIM), University "Aldo Moro" of Bari, 70124 Bari, Italy.

出版信息

J Imaging. 2024 Dec 10;10(12):315. doi: 10.3390/jimaging10120315.

DOI:10.3390/jimaging10120315
PMID:39728212
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11676445/
Abstract

This study aimed to evaluate our center's experience in diagnosing and managing placenta accreta spectrum (PAS) in a high-risk population, focusing on prenatal ultrasound features associated with PAS severity and maternal outcomes. We conducted a retrospective analysis of 102 high-risk patients with confirmed placenta previa who delivered at our center between 2018 and 2023. Patients underwent transabdominal and transvaginal ultrasound scans, assessing typical sonographic features. Binary and multivariate logistic regression analyses were performed to identify sonographic markers predictive of PAS and relative complications. Key ultrasound features-retroplacental myometrial thinning (<1 mm), vascular lacunae, and retroplacental vascularization-were significantly associated with PAS and a higher risk of surgical complications. An exceedingly rare sign, the "riddled cervix" sign, was observed in only three patients with extensive cervical or parametrial involvement. Those patients had the worst surgical outcomes. This study highlights the utility of specific ultrasound features in stratifying PAS risk and guiding clinical and surgical management in high-risk pregnancies. The findings support integrating these markers into prenatal diagnostic protocols to improve patient outcomes and inform surgical planning.

摘要

本研究旨在评估我们中心在高危人群中诊断和管理胎盘植入谱系疾病(PAS)的经验,重点关注与PAS严重程度及母体结局相关的产前超声特征。我们对2018年至2023年间在本中心分娩的102例确诊前置胎盘的高危患者进行了回顾性分析。患者接受了经腹和经阴道超声检查,评估典型的超声特征。进行二元和多变量逻辑回归分析,以确定预测PAS及相关并发症的超声标志物。关键超声特征——胎盘后肌层变薄(<1 mm)、血管腔隙和胎盘后血管形成——与PAS及手术并发症的较高风险显著相关。一种极为罕见的征象,即“宫颈筛孔样”征象,仅在3例宫颈或宫旁广泛受累的患者中观察到。这些患者的手术结局最差。本研究强调了特定超声特征在分层PAS风险及指导高危妊娠的临床和手术管理中的作用。研究结果支持将这些标志物纳入产前诊断方案,以改善患者结局并为手术规划提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33d4/11676445/55cf1c5dbd94/jimaging-10-00315-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33d4/11676445/55cf1c5dbd94/jimaging-10-00315-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33d4/11676445/55cf1c5dbd94/jimaging-10-00315-g001.jpg

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PAS or Not PAS? The Sonographic Assessment of Placenta Accreta Spectrum Disorders and the Clinical Validation of a New Diagnostic and Prognostic Scoring System.是胎盘植入还是非胎盘植入?胎盘植入谱系疾病的超声评估及一种新的诊断和预后评分系统的临床验证
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本文引用的文献

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Instrumental Diagnosis of Placenta Accreta and Obstetric and Perinatal Outcomes: Literature Review and Observational Study.胎盘植入的仪器诊断与产科及围产期结局:文献综述与观察性研究
Transl Med UniSa. 2024 Oct 1;26(2):111-121. doi: 10.37825/2239-9747.1060. eCollection 2024.
2
Cesarean hysterectomy in pregnancies complicated with placenta previa accreta: a retrospective hospital-based study.胎盘植入性前置胎盘剖宫产子宫切除术:一项回顾性基于医院的研究。
BMC Pregnancy Childbirth. 2024 Oct 2;24(1):634. doi: 10.1186/s12884-024-06834-z.
3
The sonographic assessment to diagnose Placenta Accreta Spectrum disorders: "Riddled Cervix" and other signs.
超声评估诊断胎盘植入谱系疾病:“宫颈筛孔状”及其他征象。
Arch Gynecol Obstet. 2024 Aug;310(2):1265-1266. doi: 10.1007/s00404-024-07575-2. Epub 2024 Jun 12.
4
Ultrasound scoring system for prenatal diagnosis of placenta accreta spectrum.超声评分系统用于胎盘植入谱系的产前诊断。
BMC Pregnancy Childbirth. 2023 Aug 7;23(1):569. doi: 10.1186/s12884-023-05886-x.
5
Comprehensive surgical staging for placenta accreta spectrum.胎盘植入谱系疾病的综合手术分期
J Matern Fetal Neonatal Med. 2022 Dec;35(26):10660-10666. doi: 10.1080/14767058.2022.2154572. Epub 2022 Dec 21.
6
An update of diagnostic efficacy of ultrasound and magnetic resonance imaging in the diagnosis of clinically significant placenta accreta spectrum disorders.超声和磁共振成像在诊断临床上有意义的胎盘植入谱系疾病中的诊断效能的更新。
Curr Opin Obstet Gynecol. 2022 Oct 1;34(5):287-291. doi: 10.1097/GCO.0000000000000811. Epub 2022 Jul 11.
7
Role of placenta accreta index in prediction of morbidly adherent placenta: A reliability study.胎盘植入指数在凶险性前置胎盘预测中的作用:一项可靠性研究。
Ultrasound. 2021 May;29(2):92-99. doi: 10.1177/1742271X20959742. Epub 2020 Sep 22.
8
Criteria for placenta accreta spectrum in the International Federation of Gynaecology and Obstetrics classification, and topographic invasion area are associated with massive hemorrhage in patients with placenta previa.国际妇产科联合会分类中胎盘植入谱系的标准以及局部侵犯区域与前置胎盘患者的大出血有关。
Acta Obstet Gynecol Scand. 2021 Jun;100(6):1019-1025. doi: 10.1111/aogs.14143. Epub 2021 Mar 23.
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Diagnosis and Management of Cesarean Scar Pregnancy and Placenta Accreta Spectrum: Case Series and Review of the Literature.剖宫产瘢痕妊娠和胎盘植入谱系疾病的诊断和管理:病例系列及文献复习。
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