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是胎盘植入还是非胎盘植入?胎盘植入谱系疾病的超声评估及一种新的诊断和预后评分系统的临床验证

PAS or Not PAS? The Sonographic Assessment of Placenta Accreta Spectrum Disorders and the Clinical Validation of a New Diagnostic and Prognostic Scoring System.

作者信息

Vimercati Antonella, Galante Arianna, Fanelli Margherita, Cirignaco Francesca, Vitagliano Amerigo, Nicolì Pierpaolo, Tinelli Andrea, Malvasi Antonio, Dellino Miriam, Damiani Gianluca Raffaello, Crescenza Barbara, Baldini Giorgio Maria, Cicinelli Ettore, Cerbone Marco

机构信息

Obstetrics and Gynaecology Unit, Department of Interdisciplinary Medicine (DIM), University of Bari, 70124 Bari, Italy.

Chair of Medical Statistic, Department of Interdisciplinary Medicine (DIM), University "Aldo Moro" of Bari, 70124 Bari, Italy.

出版信息

J Imaging. 2024 Dec 10;10(12):315. doi: 10.3390/jimaging10120315.

Abstract

This study aimed to evaluate our center's experience in diagnosing and managing placenta accreta spectrum (PAS) in a high-risk population, focusing on prenatal ultrasound features associated with PAS severity and maternal outcomes. We conducted a retrospective analysis of 102 high-risk patients with confirmed placenta previa who delivered at our center between 2018 and 2023. Patients underwent transabdominal and transvaginal ultrasound scans, assessing typical sonographic features. Binary and multivariate logistic regression analyses were performed to identify sonographic markers predictive of PAS and relative complications. Key ultrasound features-retroplacental myometrial thinning (<1 mm), vascular lacunae, and retroplacental vascularization-were significantly associated with PAS and a higher risk of surgical complications. An exceedingly rare sign, the "riddled cervix" sign, was observed in only three patients with extensive cervical or parametrial involvement. Those patients had the worst surgical outcomes. This study highlights the utility of specific ultrasound features in stratifying PAS risk and guiding clinical and surgical management in high-risk pregnancies. The findings support integrating these markers into prenatal diagnostic protocols to improve patient outcomes and inform surgical planning.

摘要

本研究旨在评估我们中心在高危人群中诊断和管理胎盘植入谱系疾病(PAS)的经验,重点关注与PAS严重程度及母体结局相关的产前超声特征。我们对2018年至2023年间在本中心分娩的102例确诊前置胎盘的高危患者进行了回顾性分析。患者接受了经腹和经阴道超声检查,评估典型的超声特征。进行二元和多变量逻辑回归分析,以确定预测PAS及相关并发症的超声标志物。关键超声特征——胎盘后肌层变薄(<1 mm)、血管腔隙和胎盘后血管形成——与PAS及手术并发症的较高风险显著相关。一种极为罕见的征象,即“宫颈筛孔样”征象,仅在3例宫颈或宫旁广泛受累的患者中观察到。这些患者的手术结局最差。本研究强调了特定超声特征在分层PAS风险及指导高危妊娠的临床和手术管理中的作用。研究结果支持将这些标志物纳入产前诊断方案,以改善患者结局并为手术规划提供依据。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/33d4/11676445/55cf1c5dbd94/jimaging-10-00315-g001.jpg

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