Kittipibul Thanachaporn, Dalin Chea Piseth, Masoudi Ali, Zheng Jie, Deng Sophie X
Department of Ophthalmology, Center of Excellence for Cornea and Stem Cell Transplantation, Faculty of Medicine, Chulalongkorn University, Bangkok, Thailand.
Department of Ophthalmology, Excellence Center for Cornea and Stem Cell Transplantation, King Chulalongkorn Memorial Hospital, Thai Red Cross Society, Bangkok, Thailand.
Cornea. 2025 Apr 1;44(4):405-411. doi: 10.1097/ICO.0000000000003775. Epub 2024 Dec 19.
This concise review focuses on the latest advancements in the diagnosis and management of limbal stem cell deficiency (LSCD). Ensuring the standard of care for individuals affected by LSCD involves the crucial task for physicians to meticulously and accurately diagnose the condition and determine its specific stage. A standardized diagnostic approach forms the foundation for formulating and delivering customized therapeutic interventions to maximize treatment outcomes for each patient. In this review, we introduce a systematic diagnostic algorithm to guide the assessment of LSCD. In addition, the current management algorithm and emerging therapies for LSCD are summarized.
本简要综述聚焦于角膜缘干细胞缺乏症（LSCD）诊断与管理的最新进展。确保为受LSCD影响的个体提供标准治疗，对医生而言是一项关键任务，即要细致且准确地诊断病情并确定其具体阶段。标准化的诊断方法是制定和提供定制化治疗干预措施的基础，以便为每位患者实现最佳治疗效果。在本综述中，我们引入一种系统性诊断算法以指导LSCD的评估。此外，还总结了LSCD当前的管理算法和新兴疗法。
