Reta Birhanu Kassie, Beker Abdi Mohammed, Hagos Hindeya Hailu, Weldegebriel Micheale Hailu, Kidanu Gebreyohans Tesfay, Zeray Million Abraha
Aksum University College of Health Science Department of Pathology, Aksum, Ethiopia.
Adama Hospital Medical College, Department of Pathology, Adama, Ethiopia.
Int J Surg Case Rep. 2025 Jan;126:110782. doi: 10.1016/j.ijscr.2024.110782. Epub 2024 Dec 24.
Primary mucinous cystadenoma is a very rare lesion in the spleen, with only a few reported cases available in the literature. Ectopic pancreatic or enteric tissue and invaginated splenic capsular epithelium are assumed to be the origin of mucinous cystadenomas of the spleen. We present the first reported case in Ethiopia.
A 42-year-old female patient presented with abdominal pain and swelling of one year duration, with physical examination finding of a left upper quadrant tender mass with nodular surface. An ultrasound scan revealed multiple cystic lesions in the spleen. Splenectomy was done and subsequent histopathologic examination demonstrated multiple cystic spaces lined by bland cuboidal to flat nonciliated epithelium and filled with mucin which is diagnostic of mucinous cystadenoma.
Epithelial cysts are generally rare in the spleen. Even though there are some reported cases, primary mucinous cystadenoma in the spleen is even rarer. We discussed clinicopathologic features of mucinous cystadenoma from previously published case reports.
Regardless of its rare nature, mucinous cystadenoma should be entertained as a possibility in patients with an imaging finding of cystic lesion in the spleen.
原发性黏液性囊腺瘤是脾脏中一种非常罕见的病变，文献中仅有少数病例报道。异位胰腺或肠组织以及内陷的脾包膜上皮被认为是脾脏黏液性囊腺瘤的起源。我们报告了埃塞俄比亚的首例病例。
一名42岁女性患者，出现腹痛和腹部肿胀症状达一年之久，体格检查发现左上腹有一触痛性肿块，表面呈结节状。超声扫描显示脾脏有多个囊性病变。进行了脾切除术，随后的组织病理学检查显示多个囊腔，内衬温和的立方形至扁平无纤毛上皮，充满黏液，这是黏液性囊腺瘤的诊断依据。
上皮性囊肿在脾脏中通常很少见。尽管有一些病例报道，但脾脏原发性黏液性囊腺瘤更为罕见。我们根据先前发表的病例报告讨论了黏液性囊腺瘤的临床病理特征。
尽管黏液性囊腺瘤性质罕见，但对于脾脏有囊性病变影像学表现的患者，应考虑到这种可能性。
