Tu Pei-Ning, Hung Chih-Heng, Chen Yi-Chun
Department of Ophthalmology, Cathay General Hospital, 280, Section 4, Ren-Ai Rd, Taipei, Taiwan, 106.
School of Medicine, College of Medicine, Fu Jen Catholic University, New Taipei City, Taiwan.
Graefes Arch Clin Exp Ophthalmol. 2024 Dec 27. doi: 10.1007/s00417-024-06726-0.
To investigate the relationship between the characteristics of optic disc rotation and visual field (VF) progression in patients with myopic open-angle glaucoma (OAG).
We included 53 eyes from 53 myopic OAG patients who were followed-up over a 3-year period. The characteristics of optic disc rotation including the degree of optic disc rotation, direction of optic disc rotation, and optic disc rotation-VF defect correspondence were investigated. The rates of global and regional VF progression were compared with different characteristics of optic disc rotation.
Thirty-seven eyes (69.8%) showed inferior optic disc rotation and 41 (77.4%) eyes showed optic disc rotation-VF defect correspondence. The inferiorly rotated optic discs with corresponding superior VF defect had faster VF progression in the superior peripheral region (P = 0.028) and superiorly rotated optic discs with corresponding inferior VF defect had faster VF progression in the inferior peripheral region (P = 0.031). The VF progression was restricted to the superior hemifield in the eyes with inferiorly rotated optic discs and corresponding superior VF defects.
In myopic OAG patients, the direction of optic disc rotation might predict faster VF progression in the corresponding peripheral region.
研究近视性开角型青光眼(OAG)患者视盘旋转特征与视野(VF)进展之间的关系。
我们纳入了53例近视性OAG患者的53只眼睛,随访3年。对视盘旋转特征进行研究,包括视盘旋转程度、视盘旋转方向以及视盘旋转与视野缺损的对应关系。比较不同视盘旋转特征下的整体和局部视野进展率。
37只眼(69.8%)表现为视盘向下旋转,41只眼(77.4%)表现为视盘旋转与视野缺损对应。视盘向下旋转且伴有相应上方视野缺损的眼睛,其上方周边区域视野进展更快(P = 0.028);视盘向上旋转且伴有相应下方视野缺损的眼睛,其下方周边区域视野进展更快(P = 0.031)。视盘向下旋转且伴有相应上方视野缺损的眼睛,视野进展局限于上半视野。
在近视性OAG患者中,视盘旋转方向可能预示相应周边区域更快的视野进展。