Rampen F H, van der Esch E P
J Am Acad Dermatol. 1985 Feb;12(2 Pt 1):385-8. doi: 10.1016/s0190-9622(85)80081-5.
Primary excisional biopsy is recommended as the procedure of choice whenever there is any suspicion of malignant melanoma. Evaluation of the total architecture of the lesion is necessary to make a satisfactory pathologic diagnosis and prognosis. Moreover, the risk of local tumor recurrence and metastatic potential can be increased by incisional procedures. Awareness of these potential hazards should provoke reappraisal of management of primary melanomas.
只要怀疑有恶性黑色素瘤，建议首选原发性切除活检。评估病变的整体结构对于做出满意的病理诊断和预后判断是必要的。此外，切开活检程序可能会增加局部肿瘤复发的风险和转移潜能。认识到这些潜在风险应促使对原发性黑色素瘤的治疗方法进行重新评估。
