Eldh J
Scand J Plast Reconstr Surg. 1979;13(2):341-5. doi: 10.3109/02844317909013079.
In a retrospective study of 269 cutaneous malignant melanomas in stage I the influence of biopsy on survival was studied. Sixty patients were treated with primary wide excision and 209 patients with excisional biopsy followed by wide excision. The 5-year survival rates for the two groups were 75.0% and 82.8% respectively. There was an equal distribution of prognostic factors such as thickness, level of invasion, presence of ulceration, location and maximal size of the tumours in the two groups. As excisional biopsy with subsequent wide excision gives an accurate histopathologic diagnosis and permits a more rational treatment of thin melanomas, this form of treatment is recommended.
在一项对269例I期皮肤恶性黑色素瘤的回顾性研究中，研究了活检对生存率的影响。60例患者接受了原发性广泛切除，209例患者接受了切除活检后再进行广泛切除。两组的5年生存率分别为75.0%和82.8%。两组中肿瘤的厚度、浸润深度、溃疡的存在、位置和最大尺寸等预后因素分布均衡。由于切除活检后再进行广泛切除能提供准确的组织病理学诊断，并允许对薄型黑色素瘤进行更合理的治疗，因此推荐这种治疗方式。
