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C组着色性干皮病患儿光老化及防晒行为的评估:一项前瞻性分析

Evaluation of Photoaging and Sun Protection Behavior in Children With Xeroderma Pigmentosum, Group C: A Prospective Analysis.

作者信息

Ahuja Rhea, Imran Shafaque, Swaroop Devesh Kumar Jag, Gupta Somesh, Verma Kaushal K, Sharma Namrata, Bhari Neetu

机构信息

Department of Dermatology and Venereology and Ophthalmology, All India Institute of Medical Sciences, New Delhi, India.

出版信息

Pediatr Dermatol. 2025 May-Jun;42(3):556-559. doi: 10.1111/pde.15848. Epub 2024 Dec 28.

DOI:10.1111/pde.15848
PMID:39731425
Abstract

Thirteen children with xeroderma pigmentosum variant C were evaluated using the Dermoscopic Photoaging Assessment Scale (DPAS), the Glogau scale, and the Sun Protection Behavior Scale (SPBS). Most patients exhibited signs of epidermal photoaging, with pigmentary and vascular changes and poor sun protection behavior (mean SPBS score: 18.92 ± 5.69). The mean DPAS score of 13.15 correlated with the Glogau scale and ocular severity score. Sun protection behavior improved significantly at 6 months after repeated reinforcement of sun protection measures (35 ± 5.68).

摘要

使用皮肤镜光老化评估量表(DPAS)、Glogau量表和防晒行为量表(SPBS)对13名伴有C型着色性干皮病的儿童进行了评估。大多数患者表现出表皮光老化的迹象,伴有色素沉着和血管变化,且防晒行为较差(平均SPBS评分:18.92±5.69)。平均DPAS评分为13.15,与Glogau量表及眼部严重程度评分相关。在反复强化防晒措施6个月后,防晒行为有显著改善(35±5.68)。

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