Ehman R L, Kjos B O, Hricak H, Brasch R C, Higgins C B
J Comput Assist Tomogr. 1985 Mar-Apr;9(2):315-9. doi: 10.1097/00004728-198503000-00016.
Knowledge of the normal relative intensity of organs and tissues is a valuable aid to clinical interpretation of magnetic resonance images. In this study the in vivo spin echo image intensities of normal parenchymal organs and other structures in the upper abdomen were evaluated for eight parameter combinations. The examinations of 40 patients were used. Image intensity and calculated T1, T2, and spin density values were obtained for liver, spleen, pancreas, renal cortex, renal medulla, bone marrow, skeletal muscle, and fat. Repetition times (TR) of 500, 1,000, 1,500, and 2,000 ms and echo times of 28 and 56 ms were used. The T1 and T2 values and relative spin density were calculated using a new algorithm. Liver had the smallest relative standard deviation of T1 of all the tissues studied. For comparison purposes, relative image intensities were calculated by normalizing them to the intensity of liver in the same image. The resulting compiled data show the normal ranks and ranges for relative intensity for the tissues in each of eight types of spin echo images. Although images with short TR and echo time (TE) are known to display the greatest T1 contrast, the mean relative intensities of all tissues except muscle and fat in the TR = 500 and TE = 28 ms images were within 20% of liver. A much larger spread in the normal relative intensities was observed with longer TE and TR.
了解器官和组织的正常相对强度有助于对磁共振图像进行临床解读。在本研究中,对8种参数组合下上腹部正常实质器官和其他结构的活体自旋回波图像强度进行了评估。使用了40名患者的检查数据。获取了肝脏、脾脏、胰腺、肾皮质、肾髓质、骨髓、骨骼肌和脂肪的图像强度以及计算得出的T1、T2和自旋密度值。重复时间(TR)分别为500、1000、1500和2000毫秒,回波时间为28和56毫秒。使用一种新算法计算T1和T2值以及相对自旋密度。在所研究的所有组织中,肝脏的T1相对标准差最小。为了进行比较,通过将相对图像强度归一化为同一图像中肝脏的强度来计算。所得汇总数据显示了8种类型自旋回波图像中各组织相对强度的正常排名和范围。尽管已知短TR和回波时间(TE)的图像显示出最大的T1对比度,但在TR = 500且TE = 28毫秒的图像中,除肌肉和脂肪外,所有组织的平均相对强度都在肝脏的20%以内。随着TE和TR变长,正常相对强度的分布范围明显增大。