Zhao Xiaofeng, Jia Liancheng, Li Weiguang, Xu Huichao, Ning Peng, Sha Nan, Zhang Lei
Department of Urology Surgery, Beijing Traditional Chinese Medicine Hospital Affiliated to Capital Medical University, No.23 Art Museum Back Street, Dongcheng District, Beijing, 100010, China.
Lasers Med Sci. 2024 Dec 28;40(1):2. doi: 10.1007/s10103-024-04261-2.
To compare the efficacy and safety of low-power holmium laser enucleation of the prostate (LP-HoLEP) with plasma kinetic resection of prostate (PKRP). Sixty-three patients treated with transurethral LP-HoLEP (observation group) and 68 patients treated with transurethral PKRP (control group) at Beijing Hospital of Traditional Chinese Medicine from November 2019 to November 2022 were retrospectively compared with regard to operation duration, intra-operative blood loss, prostate resection ratio, postoperative bladder irrigation time, postoperative indwelling urinary catheter time, postoperative urinary incontinence incidence, International Prostate Symptom Scale (IPSS), maximum urine flow rate (Qmax), and residual urine volume (RUV). In both groups, postoperative IPSS, Qmax, and RUV were significantly improved compared to preoperative values (P < 0.05). Comparing the observation group to the control group, the intra-operative blood loss were (59.6 ± 18.1) and (173.1 ± 85.3) ml, respectively (t = -10.350, P < 0.01); the prostate resection ratios were (81.2 ± 4.6) % and (56.7 ± 9.7)%, respectively (t = 18.230, P < 0.01); the postoperative bladder irrigation time was (39.1 ± 9.6) h and (49.7 ± 6.0) h, respectively (t = -7.623, P < 0.01); and the postoperative indwelling urinary catheter time was (111.5 ± 19.4) h and (120.4 ± 12.8) h, respectively (t = -3.125, P < 0.01). Comparing the observation group to the control group, the operation duration was (76.2 ± 18.6) and (83.0 ± 32.4) min, respectively, with no statistical difference (t = -1.226, P = 0.208); the postoperative urinary incontinence incidence was 12.7% and 8.8%, respectively and there was no statistical difference (χ² = 0.514, P = 0.473). LP-HoLEP offers excellent surgical efficacy and safety. LP-HoLEP is superior to PKRP in intra-operative blood loss, postoperative bladder irrigation time, and postoperative indwelling urinary catheter time, and can enucleate more hyperplastic glands.
比较低功率钬激光前列腺剜除术（LP-HoLEP）与等离子体前列腺切除术（PKRP）的疗效和安全性。回顾性比较2019年11月至2022年11月在北京中医医院接受经尿道LP-HoLEP治疗的63例患者（观察组）和接受经尿道PKRP治疗的68例患者（对照组）在手术时间、术中出血量、前列腺切除率、术后膀胱冲洗时间、术后留置导尿管时间、术后尿失禁发生率、国际前列腺症状评分（IPSS）、最大尿流率（Qmax）和残余尿量（RUV）等方面的情况。两组患者术后的IPSS、Qmax和RUV均较术前显著改善（P＜0.05）。观察组与对照组比较，术中出血量分别为（59.6±18.1）ml和（173.1±85.3）ml（t = -10.350，P＜0.01）；前列腺切除率分别为（81.2±4.6）%和（56.7±9.7）%（t = 18.230，P＜0.01）；术后膀胱冲洗时间分别为（39.1±9.6）h和（49.7±6.0）h（t = -7.623，P＜0.01）；术后留置导尿管时间分别为（111.5±19.4）h和（120.4±12.8）h（t = -3.125，P＜0.01）。观察组与对照组比较，手术时间分别为（76.2±18.6）min和（83.0±32.4）min，差异无统计学意义（t = -1.226，P = 0.208）；术后尿失禁发生率分别为12.7%和8.8%，差异无统计学意义（χ² = 0.514，P = 0.473）。LP-HoLEP具有出色的手术疗效和安全性。LP-HoLEP在术中出血量、术后膀胱冲洗时间和术后留置导尿管时间方面优于PKRP，且能剜除更多增生腺体。
