Hoseinzadeh Ahmad, Arani Hamid Zaferani, Tajaddini Ali, Rahimi Shekoofeh, Mirparsa Fatemeh, Hooshmandi Sedighe
Department of Surgery, Shiraz University of Medical Sciences, Shiraz, Iran.
Department of Health Policy, Faculty of Health, Scientific Pole of Health Sciences Education, Tehran Medical Sciences, Tehran University of Medical Sciences, Tehran, Iran.
Int J Surg Case Rep. 2025 Jan;126:110791. doi: 10.1016/j.ijscr.2024.110791. Epub 2024 Dec 26.
The persistent sciatic artery (PSA) is a rare congenital vascular anomaly that arises when the embryonic axial artery fails to regress, potentially leading to serious complications such as limb ischemia.
We report the case of a 47-year-old woman with a history of essential hypertension and recent hormonal treatment for uterine fibroids. She developed acute limb ischemia due to bilateral PSA thrombosis, which was confirmed through comprehensive imaging. A multidisciplinary team implemented a management strategy that included anticoagulation therapy and close monitoring, resulting in significant improvement in her symptoms.
The incidence of PSA thrombosis is low, estimated at around 0.04 % to 0.06 %, with bilateral involvement in approximately 30 % of cases. This case underscores the importance of individualized treatment plans and highlights the need for increased awareness and research into PSA to optimize clinical outcomes, particularly in resource-limited settings.
This report emphasizes the critical role of early diagnosis and a tailored approach to management in patients with PSA.
永存坐骨动脉（PSA）是一种罕见的先天性血管异常，当胚胎轴动脉未能退化时就会出现，可能导致肢体缺血等严重并发症。
我们报告了一名47岁女性的病例，她有原发性高血压病史，近期因子宫肌瘤接受激素治疗。她因双侧PSA血栓形成而发生急性肢体缺血，通过综合影像学检查得以确诊。一个多学科团队实施了包括抗凝治疗和密切监测在内的管理策略，使她的症状有了显著改善。
PSA血栓形成的发生率较低，估计约为0.04%至0.06%，约30%的病例为双侧受累。该病例强调了个体化治疗方案的重要性，并突出了提高对PSA的认识和研究以优化临床结果的必要性，特别是在资源有限的环境中。
本报告强调了早期诊断和针对PSA患者的定制管理方法的关键作用。
