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在结局监测中减轻患者负担:PHQ-9、GAD-7和WSAS简化版的实例

Minimizing patient burden in outcome monitoring: The case for abbreviated versions of PHQ-9, GAD-7 and WSAS.

作者信息

Smith Otto R F, Knapstad Marit, Aarø Leif Edvard

机构信息

Department of Health Promotion, Norwegian Institute of Public Health, Zander Kaaes gate 7, 5015 Bergen, Norway; Centre for Evaluation of Public Health Measures, Norwegian Institute of Public Health, Norway; Department of Teacher Education, NLA University College, Bergen, Pb 74 Sandviken, 5812 Bergen, Norway.

Department of Health Promotion, Norwegian Institute of Public Health, Zander Kaaes gate 7, 5015 Bergen, Norway.

出版信息

J Affect Disord. 2025 Mar 15;373:237-244. doi: 10.1016/j.jad.2024.12.089. Epub 2024 Dec 26.

Abstract

BACKGROUND

The Improving Access to Psychological Therapies (IAPT) program uses the Patient Health Questionnaire (PHQ-9), the Generalized Anxiety Disorder Scale (GAD-7), and the Work and Social Adjustment Scale (WSAS) as part of their unique outcome monitoring system. To reduce patient burden, this study explored whether abbreviated versions of these questionnaires can be used to derive relevant outcome statistics with minimal loss of information.

METHODS

Using two samples (training; n = 1530, validation; n = 766), we examined whether existing short-forms, PHQ-4 and GAD-R3, would provide enough information to calculate relevant outcomes with near perfect agreement with the outcomes based on the original scales. We also examined 1) whether additional items would further improve the agreement between the abbreviated and original scales, and 2) alternative short-forms based on the sample-derived item information curves. The latter was also used to derive an abbreviated version of WSAS.

RESULTS

The abbreviated version derived from the item information curves provided the closest match with the original scales. A 5-item version of PHQ, a 4-item version of GAD, and a 3-item version of WSAS were correlated 0.95 with their original counterpart. Agreement as expressed by Cohen's kappa also suggested near perfect agreement for the outcomes (reliable) recovery rate and reliable improvement rate (>0.80). The outcome point estimates also matched very well (<2 % difference). Results were replicated in the validation sample.

CONCLUSION

The derived abbreviated versions can be used for the purpose of routine outcome monitoring with minimal loss of information and reduce patient burden with nearly 50 %.

摘要

背景

改善心理治疗可及性(IAPT)项目使用患者健康问卷(PHQ - 9)、广泛性焦虑障碍量表(GAD - 7)和工作与社会适应量表(WSAS)作为其独特结果监测系统的一部分。为减轻患者负担,本研究探讨了这些问卷的简化版本是否可用于得出相关结果统计数据,同时信息损失最小。

方法

我们使用两个样本(训练样本;n = 1530,验证样本;n = 766),检验现有的简化版,即PHQ - 4和GAD - R3,是否能提供足够信息来计算相关结果,且与基于原始量表得出的结果几乎完全一致。我们还检验了:1)额外的条目是否会进一步提高简化版与原始量表之间的一致性;2)基于样本衍生的条目信息曲线的替代简化版。后者还用于得出WSAS的简化版。

结果

从条目信息曲线得出的简化版与原始量表的匹配度最高。PHQ的5条目版、GAD的4条目版和WSAS的3条目版与各自的原始版本的相关性为0.95。用科恩kappa系数表示的一致性也表明,结果(可靠)恢复率和可靠改善率(>0.80)几乎完全一致。结果点估计也非常匹配(差异<2%)。结果在验证样本中得到重复。

结论

得出的简化版可用于常规结果监测,信息损失最小,且可将患者负担减轻近50%。

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