Herbawi Abdalrahman N, Azzam Saif K, AboGhayyada Ibrahim, Hroub Osama, Ibraheem Kareem, Eltamimi Badawi
Faculty of Medicine, Palestine Polytechnic University, Hebron 90200, Palestine.
Faculty of Medicine, Palestine Polytechnic University, Hebron 90200, Palestine; Palestinian Clinical Research Center, Bethlehem, Palestine.
Int J Surg Case Rep. 2025 Jan;126:110746. doi: 10.1016/j.ijscr.2024.110746. Epub 2024 Dec 15.
Esophageal leiomyoma is the most common benign submucosal mesenchymal tumor of the esophagus, typically asymptomatic but can cause symptoms such as dysphagia, chest pain, or regurgitation when large. Diagnosis is often incidental, confirmed by imaging techniques like computed tomography (CT) and endoscopic ultrasound (EUS), with surgical enucleation being the standard treatment.
A 28-year-old male presented with a one-year history of persistent epigastric discomfort and gastroesophageal reflux disease (GERD) symptoms unresponsive to proton pump inhibitors. Chest radiograph and CT scan revealed a well-defined submucosal mass in the esophagus. Upper gastrointestinal endoscopy and EUS confirmed the lesion's benign nature. Fine-needle aspiration biopsy showed spindle-shaped cells, confirming esophageal leiomyoma. The patient underwent minimally invasive tumor resection via video-assisted thoracoscopic surgery (VATS), with a smooth postoperative recovery.
Esophageal leiomyomas are rare, often asymptomatic, and may present with nonspecific symptoms if large. CT and EUS are key diagnostic tools, and minimally invasive surgery, such as VATS, is the preferred treatment for larger tumors due to shorter recovery times and fewer complications. Early identification and appropriate surgical intervention are crucial for optimal outcomes.
Esophageal leiomyoma should be considered in patients with GERD-like symptoms unresponsive to therapy. Early imaging, endoscopic evaluation, and minimally invasive surgery provide excellent outcomes, with regular follow-up recommended to monitor for recurrence.
食管平滑肌瘤是食管最常见的良性黏膜下间质瘤,通常无症状,但较大时可引起吞咽困难、胸痛或反流等症状。诊断多为偶然发现,通过计算机断层扫描(CT)和内镜超声(EUS)等成像技术确诊,手术摘除是标准治疗方法。
一名28岁男性,有一年持续性上腹部不适病史,且患有胃食管反流病(GERD),对质子泵抑制剂无反应。胸部X线片和CT扫描显示食管有一个边界清晰的黏膜下肿块。上消化道内镜检查和EUS证实了病变的良性性质。细针穿刺活检显示梭形细胞,确诊为食管平滑肌瘤。患者通过电视辅助胸腔镜手术(VATS)进行了微创肿瘤切除,术后恢复顺利。
食管平滑肌瘤罕见,通常无症状,较大时可能出现非特异性症状。CT和EUS是关键的诊断工具,对于较大肿瘤,由于恢复时间短且并发症少,微创外科手术如VATS是首选治疗方法。早期识别和适当的手术干预对于获得最佳结果至关重要。
对于治疗无反应的类似GERD症状的患者,应考虑食管平滑肌瘤。早期成像、内镜评估和微创外科手术可带来良好的结果,建议定期随访以监测复发情况。