da Silva Rodrigues Guilherme, da Silva Sobrinho Andressa Crystine, Costa Gabriel Peinado, da Silva Leonardo Santos Lopes, de Lima João Gabriel Ribeiro, da Silva Gonçalves Leonardo, Finzeto Larissa Chacon, Bueno Júnior Carlos Roberto
Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Department of Internal Medicine, Ribeirão Preto Medical School, University of São Paulo, Ribeirão Preto, São Paulo, Brazil.
Exp Gerontol. 2025 Feb;200:112669. doi: 10.1016/j.exger.2024.112669. Epub 2025 Jan 2.
This study employed multivariate analysis to investigate the effects of a 14-week multicomponent training program on sedentary adults and older populations, focusing on improvements in physical fitness, health markers, and anthropometric measures. The data included 376 participants aged 30 to 84 years who had been inactive for at least 3 months. Results showed that participants aged 71 and above had lower systolic blood pressure, height, body mass, elbow flexion and extension, sitting and standing up from a chair, agility, 6-Minute Walk Test (6MWT), and handgrip strength values compared to younger age groups (p < 0.05). Initially, the 6MWT was inversely correlated with anthropometric measures and positively correlated with strength tests, but after the intervention, it remained correlated only with handgrip strength and agility. Interestingly, the elbow flexion and extension strongly correlated with other fitness measures pre-intervention, but these relationships weakened afterward. Agility became a key intermediary variable in the analysis. Despite improvements, anthropometric variables like body mass and waist circumference continued to have a strong relationship with fitness outcomes. Significant gains were observed in the 6MWT and elbow flexion and extension (p < 0.05), indicating improvements in aerobic fitness and strength. Multivariate analysis showed that hip circumference, chair stand test, handgrip strength, and agility significantly influenced 6MWT performance. Using multivariate analysis, we were able to highlight the importance of incorporating regular exercise into daily life to promote active and healthy aging. Furthermore, agility emerged as the most significant intermediate variable after the intervention. This insight suggests that improvements in agility may be crucial for physical fitness and overall health.
本研究采用多变量分析方法,调查了一项为期14周的多组分训练计划对久坐不动的成年人及老年人群体的影响,重点关注身体素质、健康指标和人体测量指标的改善情况。数据包括376名年龄在30至84岁之间、至少3个月未进行运动的参与者。结果显示,与年轻年龄组相比,71岁及以上的参与者收缩压、身高、体重、肘部屈伸、从椅子上坐起和站起、敏捷性、6分钟步行试验(6MWT)以及握力值较低(p < 0.05)。最初,6MWT与人体测量指标呈负相关,与力量测试呈正相关,但干预后,它仅与握力和敏捷性相关。有趣的是,干预前肘部屈伸与其他身体素质指标密切相关,但之后这些关系减弱。敏捷性在分析中成为关键的中介变量。尽管有所改善,但体重和腰围等人体测量变量与健康结果仍有很强的关联。6MWT以及肘部屈伸有显著提高(p < 0.05),表明有氧适能和力量有所改善。多变量分析表明,臀围、椅子站立试验、握力和敏捷性显著影响6MWT表现。通过多变量分析我们能够强调将定期锻炼纳入日常生活以促进积极健康老龄化的重要性。此外,干预后敏捷性成为最显著的中介变量。这一见解表明,敏捷性的改善可能对身体素质和整体健康至关重要。