Rocha Aurélio de Oliveira, Favoreto Michael Willian, Menezes Dos Anjos Lucas, Henriques Bruno, Loguercio Alessandro D, Reis Alessandra, Cardoso Mariane
Department of Dentistry, Federal University of Santa Catarina, Florianopolis, Santa Catarina, Brazil.
Department of Restorative Dentistry, State University of Ponta Grossa, Ponta Grossa, Paraná, Brazil; Department of Restorative Dentistry, Tuiuti University of Parana, Curitiba, Paraná, Brazil.
J Dent. 2025 Feb;153:105550. doi: 10.1016/j.jdent.2024.105550. Epub 2024 Dec 27.
The aim of this study was to analyze the characteristics and trends of publications in clinical trials on tooth bleaching through a bibliometric and altmetric analysis.
A search was conducted in September 2024 on Web of Science Core Collection (WoS-CC) and Scopus. Two researchers selected articles and extracted key study characteristics. VOSviewer was used to generate bibliometric networks. Dimensions was consulted to measure altmetric data.
416 studies were included, published between 1990 and 2024. The most cited study obtained 164 citations on WoS-CC and 201 on Scopus. The studies predominantly investigated bleaching efficacy (n = 232), often employing double-blind designs (n = 146), conducted in adults (n = 403), randomized (n = 307), and mainly using hydrogen peroxide (n = 200) for at-home vital dental bleaching (n = 199). The majority of the articles were published by Brazilian authors (n = 165), with Loguercio AD (n = 70) and Reis A (n = 56) being the most frequent authors. The manufacturer FGM led with the highest number of investigated products (n = 153), particularly highlighting Whiteness HP Maxx 35 % (n = 40). VOSviewer revealed significant collaborations among authors and keywords. According to Dimensions, users of Mendeley and news outlets have shown great interest in whitening clinical trials.
This study highlighted a growing trend in clinical trials on tooth bleaching over 30 years, with a strong predominance of studies conducted in Brazil that primarily investigated bleaching efficacy through double-blind designs in adults using hydrogen peroxide.
Clinical trials on tooth bleaching represent one of the highest levels of scientific evidence guiding clinical practice, thus requiring thorough evaluation.
本研究旨在通过文献计量学和替代计量学分析，剖析牙齿漂白临床试验出版物的特征和趋势。
2024年9月在科学网核心合集（WoS-CC）和Scopus上进行检索。两名研究人员筛选文章并提取关键研究特征。使用VOSviewer生成文献计量网络。查阅Dimensions以衡量替代计量数据。
纳入了1990年至2024年间发表的416项研究。被引用次数最多的研究在WoS-CC上获得164次引用，在Scopus上获得201次引用。这些研究主要调查漂白效果（n = 232），常采用双盲设计（n = 146），在成人中进行（n = 403），随机分组（n = 307），且主要使用过氧化氢（n = 200）进行家庭内活髓牙齿漂白（n = 199）。大多数文章由巴西作者发表（n = 165），其中Loguercio AD（n = 70）和Reis A（n = 56）是最常出现的作者。制造商FGM所涉研究产品数量最多（n = 153），尤其突出的是Whiteness HP Maxx 35%（n = 40）。VOSviewer揭示了作者和关键词之间的显著合作关系。根据Dimensions，Mendeley用户和新闻媒体对美白临床试验表现出极大兴趣。
本研究突出了30年来牙齿漂白临床试验的增长趋势，巴西进行的研究占主导地位，这些研究主要通过双盲设计在成人中使用过氧化氢调查漂白效果。
牙齿漂白临床试验是指导临床实践的最高科学证据水平之一，因此需要进行全面评估。
