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基于当前证据的牙齿漂白临床决策:一项叙述性综述。

Clinical decision-making in tooth bleaching based on current evidence: A narrative review.

作者信息

Kury Matheus, Prunes Bianca Bem, Saraceni Cintia Helena C, Hilgert Leandro Augusto, Fronza Bruna M, Lima Adriano F

机构信息

Dental Research Division, Paulista University, Sao Paulo, Brazil, Rua Doutor Bacelar, 1212, Sao Paulo 04026-002 Brazil..

Dental Research Division, Paulista University, Sao Paulo, Brazil, Rua Doutor Bacelar, 1212, Sao Paulo 04026-002 Brazil.; School of Dental Medicine, Albert Einstein Israelite Hospital, São Paulo, SP, Brazil.

出版信息

Dent Mater. 2025 May;41(5):536-552. doi: 10.1016/j.dental.2025.03.002. Epub 2025 Mar 13.

DOI:10.1016/j.dental.2025.03.002
PMID:40082147
Abstract

OBJECTIVE

This review consolidates current knowledge on dentist-supervised tooth bleaching for vital teeth, drawing from systematic reviews, meta-analyses, and randomized clinical trials (RCTs) that followed CONSORT guidelines.

DATA RESOURCES

MeSH and free terms like "tooth bleaching," "tooth whitening," "randomized clinical trial," and "systematic review" were used in PubMed, Scopus, and Web of Science databases STUDY SELECTION: Out of 839 articles, 444 were selected for full-text review, excluding case reports, non-randomized trials, literature reviews and those not directly related to tooth bleaching or RCTs not following CONSORT 2010. The remaining 203 studies were used to compare the dentist-supervised at-home and in-office clinical protocols, assessing factors such as color change, tooth sensitivity, and gingival irritation. In vitro studies were cited to support and explain basic concepts of different clinical decisions CONCLUSIONS: Daily at-home bleaching with 10 % carbamide peroxide or lower-concentration hydrogen peroxide over three to four weeks is effective. In-office bleaching with high-concentration hydrogen peroxide exhibits variations in protocols based on the HP concentration and gel's pH. Emerging technologies like violet LEDs and photobiomodulation with infrared lasers show promise in enhancing efficacy and reducing sensitivity, respectively, though more research is needed. The review underscores the importance of ongoing research into desensitization strategies to manage sensitivity related to bleaching.

CLINICAL SIGNIFICANCE

Tooth bleaching is central to dental aesthetics, offering a range of options that can challenge clinicians. Adverse effects, particularly sensitivity, highlight the need for practice supported in protocols clinically tested and effective desensitization approaches.

摘要

目的

本综述整合了关于牙医监督下活髓牙牙齿漂白的现有知识,这些知识来源于遵循CONSORT指南的系统评价、荟萃分析和随机临床试验(RCT)。

数据来源

在PubMed、Scopus和Web of Science数据库中使用了医学主题词(MeSH)以及“牙齿漂白”“牙齿美白”“随机临床试验”和“系统评价”等自由词。

研究选择

在839篇文章中,444篇被选进行全文审查,排除了病例报告、非随机试验、文献综述以及那些与牙齿漂白不直接相关或未遵循2010年CONSORT的RCT。其余203项研究用于比较牙医监督下的家庭和诊室临床方案,评估诸如颜色变化、牙齿敏感性和牙龈刺激等因素。引用体外研究来支持和解释不同临床决策的基本概念。

结论

在三到四周内每天在家使用10%过氧化脲或低浓度过氧化氢进行漂白是有效的。使用高浓度过氧化氢进行诊室漂白时,方案会因过氧化氢浓度和凝胶pH值的不同而有所变化。紫色发光二极管和红外激光光生物调节等新兴技术分别在提高疗效和降低敏感性方面显示出前景,不过还需要更多研究。该综述强调了持续研究脱敏策略以应对与漂白相关的敏感性问题的重要性。

临床意义

牙齿漂白是牙科美学的核心,提供了一系列可能给临床医生带来挑战的选择。不良反应,尤其是敏感性,凸显了在经过临床测试的方案和有效的脱敏方法支持下进行实践的必要性。

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Dent Mater. 2025 May;41(5):536-552. doi: 10.1016/j.dental.2025.03.002. Epub 2025 Mar 13.
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