Mathur Kartikeya, Birda Chhagan Lal, Singh Satyam Kumar, Uppuv Vvienodd, Kashyap Shubham, Agarwal Ashish
Department of Gastroenterology, All India Institute of Medical Sciences, Jodhpur, India.
ACG Case Rep J. 2024 Dec 27;12(1):e01578. doi: 10.14309/crj.0000000000001578. eCollection 2025 Jan.
Cytomegalovirus (CMV) and Epstein-Barr virus (EBV) are important causes of viral esophagitis mainly in immunocompromised individuals. Both viruses lead to development of focal ulcerations in the esophagus. While there have been rare case reports of esophagitis in immunocompetent individuals, there has not been a single reported case of coinfection with both CMV and EBV in an immunocompetent individual and presenting with diffuse esophageal ulceration. We report a case of severe diffuse ulcerative esophagitis caused by EBV/CMV coinfection in an immunocompetent individual.
巨细胞病毒（CMV）和爱泼斯坦-巴尔病毒（EBV）是导致病毒性食管炎的重要病因，主要见于免疫功能低下的个体。这两种病毒均可导致食管出现局灶性溃疡。虽然有罕见的免疫功能正常个体发生食管炎的病例报告，但尚无免疫功能正常个体同时感染CMV和EBV并出现弥漫性食管溃疡的病例报告。我们报告一例免疫功能正常个体因EBV/CMV合并感染导致严重弥漫性溃疡性食管炎的病例。
