Loizides Sotiris, Samouti Paraskevi, Tsironis George, Xenophontos Eleni, Papamichael Demetrios, Vassiliou Vassilios
Department of Medical Oncology, Bank of Cyprus Oncology Center, 32 Acropoleos Avenue, Nicosia 2011, Cyprus.
Department of Radiation Oncology, Bank of Cyprus Oncology Center, 32 Acropoleos Avenue, Nicosia 2011, Cyprus.
Oxf Med Case Reports. 2024 Dec 28;2024(12):omae158. doi: 10.1093/omcr/omae158. eCollection 2024 Dec.
SANT is a rare, non-lymphoid, benign entity, originating from the red pulp of the spleen. It is characterized by the presence of vascular nodules surrounded by a stroma of collagen fibers. It was introduced as a distinct disease entity by Martel et al in 2004, after the histopathological examination of 25 cases. Symptoms are unspecific, and in most cases, it is incidentally diagnosed, mostly in patients who undergo imaging for other underlying conditions. Moreover, radiological findings are usually inconclusive, and a definite diagnosis is established through histopathological examination. We herein report the case of a 76-year-old female diagnosed with stage I rectal cancer who was subsequently diagnosed with a splenic lesion after a Computed Tomography (CT) scan that was performed for follow-up purposes. Different imaging modalities were employed for further assessment; however, findings were inconclusive and the possibility of metastatic disease could not be excluded. The patient was referred for splenectomy and the diagnosis of SANT was established through histopathological examination.
脾脏血管结节样转化（SANT）是一种罕见的非淋巴性良性病变，起源于脾脏红髓。其特征是存在被胶原纤维基质包围的血管结节。2004年，Martel等人在对25例病例进行组织病理学检查后，将其作为一种独特的疾病实体引入。症状不具有特异性，在大多数情况下，是偶然诊断出来的，大多是在因其他潜在疾病接受影像学检查的患者中发现。此外，影像学检查结果通常不明确，需通过组织病理学检查才能确诊。我们在此报告一例76岁女性病例，该患者最初被诊断为I期直肠癌，随后在为进行随访而进行的计算机断层扫描（CT）中被诊断出脾脏病变。采用了不同的影像学检查方法进行进一步评估；然而，检查结果不明确，不能排除转移性疾病的可能性。该患者接受了脾切除术，通过组织病理学检查确诊为脾脏血管结节样转化。
