Dabas Rajeshwari, Dabas Ajay Kumar, Arora Sandeep, Kumar Suhag Devinder
Director MS (P), Office of DGMS (Army), New Delhi, India.
Senior Advisor (Surgery) & Vascular Surgeon, Army Hospital (R & R), New Delhi, India.
Med J Armed Forces India. 2024 Dec;80(Suppl 1):S185-S191. doi: 10.1016/j.mjafi.2023.04.003. Epub 2023 May 25.
Chronic venous insufficiency (CVI) causes cutaneous changes. This prospective observational study reveals dermoscopic findings in CVI.
Successive CVI patients of ≥18 years were included in the study. American Venous Forum classification for CVI was utilized. All underwent clinical examination, duplex ultrasound, and dermoscopy. Pregnancy, pedal edema, or pigmentation from causes other than CVI, active/healed venous ulcers, prior venous interventions, arterial insufficiency, and deep vein thrombosis were excluded.
Eighty patients were studied. Fifty-six were males [mean age of 58.9 years (SD-12.09)], and twenty-four were females [mean age of 53.9 years (SD-12.8)]. Sixty-two had bilateral, and eighteen had one limb involvement (total 142 limbs). Pigmentation was observed in 120 limbs, varicose veins in 138 limbs, eczema in 45, and edema in 33 limbs. On dermoscopy, the pigment network was accentuated and diffuse in 105 limbs and accentuated but patchy in 16 limbs. Vessel morphology noted were dotted vessels in 67 limbs, linear curved vessels in 45 limbs, linear curved vessels with branches in 11 limbs, and linear vessels in 7 limbs. Scales were white and diffuse in 56 limbs and white but patchy in 8 limbs. White and brown focal structureless areas were seen in 20 and 18 limbs, respectively. Blue-grey linear cords were seen in 34 and blue-grey clods in 6 limbs.
CVI causes changes in vessel morphology, pigmentary, and scaling patterns in the skin which are picked up by dermoscopy. Further longitudinal studies could provide insight into the temporal progression of CVI.
慢性静脉功能不全(CVI)会导致皮肤变化。这项前瞻性观察研究揭示了CVI的皮肤镜检查结果。
≥18岁的连续CVI患者被纳入研究。采用美国静脉论坛CVI分类法。所有患者均接受了临床检查、双功超声检查和皮肤镜检查。排除妊娠、足部水肿或非CVI引起的色素沉着、活动性/已愈合的静脉溃疡、既往静脉干预、动脉功能不全和深静脉血栓形成。
研究了80例患者。56例为男性[平均年龄58.9岁(标准差-12.09)],24例为女性[平均年龄53.9岁(标准差-12.8)]。62例为双侧受累,18例为单肢受累(共142条肢体)。120条肢体观察到色素沉着,138条肢体有静脉曲张,45条肢体有湿疹,33条肢体有水肿。在皮肤镜检查中,105条肢体的色素网增强且弥漫,16条肢体的色素网增强但呈斑片状。观察到的血管形态为67条肢体有点状血管,45条肢体有线性弯曲血管,11条肢体有带分支的线性弯曲血管,7条肢体有线性血管。56条肢体的鳞屑为白色且弥漫,8条肢体的鳞屑为白色但呈斑片状。分别在20条和18条肢体中观察到白色和棕色局灶性无结构区域。34条肢体可见蓝灰色线性条索,6条肢体可见蓝灰色团块。
CVI会导致皮肤血管形态、色素沉着和鳞屑模式发生变化,这些变化可通过皮肤镜检查发现。进一步的纵向研究可以深入了解CVI的时间进展情况。