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本文引用的文献

1
Burden of Talaromyces marneffei infection in people living with HIV/AIDS in Asia during ART era: a systematic review and meta-analysis.ART 时代亚洲 HIV/AIDS 患者中马尔尼菲篮状菌感染负担:系统评价和荟萃分析。
BMC Infect Dis. 2020 Jul 29;20(1):551. doi: 10.1186/s12879-020-05260-8.
2
Talaromyces marneffei Outside Endemic Areas in India: an Emerging Infection with Atypical Clinical Presentations and Review of Published Reports from India.印度非流行地区马尔尼菲青霉菌病:一种具有非典型临床表现的新发感染,并对印度发表的报告进行回顾。
Mycopathologia. 2020 Oct;185(5):893-904. doi: 10.1007/s11046-019-00420-0. Epub 2020 Jan 1.
3
Clinical Characteristics and Prognosis of Penicilliosis Among Human Immunodeficiency Virus-Infected Patients in Eastern China.中国东部地区人类免疫缺陷病毒感染患者青霉病的临床特征与预后
Am J Trop Med Hyg. 2017 Jun;96(6):1350-1354. doi: 10.4269/ajtmh.16-0521.
4
A Trial of Itraconazole or Amphotericin B for HIV-Associated Talaromycosis.伊曲康唑或两性霉素 B 治疗 HIV 相关足放线病菌病的试验。
N Engl J Med. 2017 Jun 15;376(24):2329-2340. doi: 10.1056/NEJMoa1613306.
5
Penicillium marneffei infection: an emerging disease in mainland China.马尔尼菲青霉感染:中国大陆出现的一种新疾病。
Mycopathologia. 2013 Feb;175(1-2):57-67. doi: 10.1007/s11046-012-9577-0. Epub 2012 Sep 17.
6
Epidemiology, seasonality, and predictors of outcome of AIDS-associated Penicillium marneffei infection in Ho Chi Minh City, Viet Nam.越南胡志明市艾滋病相关马尔尼菲青霉菌感染的流行病学、季节性和预后预测因素。
Clin Infect Dis. 2011 Apr 1;52(7):945-52. doi: 10.1093/cid/cir028.
7
Common reservoirs for Penicillium marneffei infection in humans and rodents, China.中国人类和啮齿动物中马尔尼菲青霉感染的常见储主。
Emerg Infect Dis. 2011 Feb;17(2):209-14. doi: 10.3201/eid1702.100718.
8
Aetiology of cavitary lung lesions in patients with HIV infection.HIV 感染者肺部空洞性病变的病因。
HIV Med. 2009 Mar;10(3):191-8. doi: 10.1111/j.1468-1293.2008.00674.x. Epub 2009 Jan 7.
9
Penicillium marneffei infection and recent advances in the epidemiology and molecular biology aspects.马尔尼菲青霉感染及流行病学和分子生物学方面的最新进展。
Clin Microbiol Rev. 2006 Jan;19(1):95-110. doi: 10.1128/CMR.19.1.95-110.2006.
10
Disseminated Penicillium marneffei infection among HIV-infected patients in Manipur state, India.印度曼尼普尔邦艾滋病毒感染患者中的播散性马尔尼菲青霉感染。
J Infect. 2002 Nov;45(4):268-71. doi: 10.1053/jinf.2002.1062.

播散性足分支菌病:是真的罕见还是未被普遍认识?

Disseminated talaromycosis: Truly uncommon or uncommonly recognized?

作者信息

Harika Padamata, Asthana Bhushan, Vashisht Rohit, Yadav Naveen, Hazra Nandita, Manrai Manish, Menon Anil S

机构信息

Resident, Department of Internal Medicine, Armed Forces Medical College, Pune, India.

Consultant (Pathology), Command Hospital (Southern Command), Pune, India.

出版信息

Med J Armed Forces India. 2024 Dec;80(Suppl 1):S247-S251. doi: 10.1016/j.mjafi.2022.12.008. Epub 2023 Jan 30.

DOI:10.1016/j.mjafi.2022.12.008
PMID:39734831
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11670531/
Abstract

34 years old male from north-east India, a known case of retroviral disease, presented with shortness of breath and significant weight loss and was found to have pancytopenia, skin lesions, organomegaly, generalized lymphadenopathy, cavitary lung disease with very low CD4 counts. He failed to improve on empirical antitubercular therapy and further evaluation revealed features of disseminated talaromycosis on bone marrow studies. We hereby present an interesting case of a systemic fungal disease in the setting of advanced HIV infection.

摘要

一名来自印度东北部的34岁男性,已知患有逆转录病毒疾病,出现呼吸急促和明显体重减轻,被发现全血细胞减少、皮肤病变、器官肿大、全身淋巴结病、有空洞的肺部疾病且CD4计数极低。他接受经验性抗结核治疗后病情未改善,进一步评估发现骨髓检查有播散性鼻孢子菌病的特征。我们在此报告一例晚期HIV感染背景下的系统性真菌病的有趣病例。