Verma Arjun, Patnaik Suprabha K, Suryawanshi Pradeep
Assistant Professor (Neonatology), Mahatma Gandhi Medical College & Hospital, Jaipur, India.
Associate Professor (Neonatology), Bharati Vidyapeeth Medical College, Deemed to be University, Pune, India.
Med J Armed Forces India. 2024 Dec;80(Suppl 1):S268-S271. doi: 10.1016/j.mjafi.2023.01.010. Epub 2023 Mar 16.
, an environmentally ubiquitous microbe, is a challenging opportunistic pathogen in the hospital setting. Neonates are particularly vulnerable to infection with but information on presentation, therapeutic response and outcome of such infection in this population is limited. To expand this knowledge, we report here a series of five cases. All the five neonates having sepsis, were preterms (27-32 weeks), very low birth weight, with clinical presentation within three weeks of life, with respiratory involvement presenting as respiratory distress due to pulmonary haemorrhage, non-specific features like lethargy, altered blood sugar levels and haemodynamic instability. The microbe was sensitive to amikacin, ceftazidime, cotrimoxazole, gentamycin, levofloxacin and minocycline except in two cases showing levofloxacin resistance. All but one neonate survived with morbidities like retinopathy of prematurity, bronchopulmonary dysplasia and metabolic bone disease.
是一种在环境中普遍存在的微生物，在医院环境中是一种具有挑战性的机会性致病菌。新生儿特别容易感染 ，但关于该人群中此类感染的临床表现、治疗反应和结局的信息有限。为了扩展这方面的知识，我们在此报告一系列五例病例。所有五例患有败血症的新生儿均为早产儿（27 - 32周），出生体重极低，在出生后三周内出现临床表现，呼吸系统受累表现为因肺出血导致的呼吸窘迫，还有诸如嗜睡、血糖水平改变和血流动力学不稳定等非特异性特征。除两例对左氧氟沙星耐药外，该微生物对阿米卡星、头孢他啶、复方新诺明、庆大霉素、左氧氟沙星和米诺环素敏感。除一名新生儿外，所有新生儿均存活，但伴有诸如早产儿视网膜病变、支气管肺发育不良和代谢性骨病等疾病。
