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杜安眼球后退综合征:两例报告及文献复习

Duane Retraction Syndrome: A Report of Two Cases and Review of Literature.

作者信息

Abu Melha Abdullah, Abbas Abdullah I, Alghamdi Wejdan S, Alghamdi Shima M, Alkhathami Abdulmajeed

机构信息

Department of Ophthalmology, King Fahad Hospital, Al Baha Health Cluster, Al Baha, SAU.

Faculty of Medicine, Ibn Sina College, Jeddah, SAU.

出版信息

Cureus. 2024 Nov 25;16(11):e74460. doi: 10.7759/cureus.74460. eCollection 2024 Nov.

Abstract

Stilling-Duane syndrome, a congenital condition characterized by aberrant innervation of the lateral rectus muscle and agenesis of the abducent nerve or its nucleus, results in limited horizontal eye movements. It is often misdiagnosed as acquired abducent nerve paralysis. This report highlights the importance of considering Stilling-Duane syndrome in differential diagnoses. Case 1 is a 26-year-old female who presented to the Ophthalmology Clinic with recurrent ocular pain and puffiness over one month. She reported discomfort in both eyes, redness, and eyelid swelling but denied double vision or any significant medical history. Examination revealed normal visual acuity, marked restriction of abduction in the left eye, and asymmetry in palpebral fissure height during adduction. Horizontal nystagmus was noted at extreme abduction of the right eye. Case 2 is a 12-year-old female presented to the Ophthalmology Clinic with decreased vision in the left eye. Examination revealed decreased visual acuity in the left eye, marked restriction of abduction in the left eye, and asymmetry in palpebral fissure height during adduction. Given our patients' diagnosis of Duane retraction syndrome (DRS) type 1 with normal head posture, a management plan of observation was recommended. Surgical intervention may be considered in the future if significant changes such as abnormal head position or strabismus occur. This case emphasizes the need for careful evaluation of congenital eye movement disorders to avoid misdiagnosis and ensure appropriate management.

摘要

施蒂林-杜安综合征是一种先天性疾病,其特征为外直肌神经支配异常以及展神经或其神经核发育不全,导致水平眼球运动受限。它常被误诊为后天性展神经麻痹。本报告强调了在鉴别诊断中考虑施蒂林-杜安综合征的重要性。病例1是一名26岁女性,因复发性眼痛和眼部肿胀一个多月前来眼科门诊就诊。她称双眼不适、发红和眼睑肿胀,但否认有复视或任何重大病史。检查发现视力正常,左眼外展明显受限,内收时睑裂高度不对称。右眼极度外展时可见水平眼球震颤。病例2是一名12岁女性,因左眼视力下降前来眼科门诊就诊。检查发现左眼视力下降,左眼外展明显受限,内收时睑裂高度不对称。鉴于我们的患者被诊断为1型杜安退缩综合征(DRS)且头部姿势正常,建议采取观察的管理方案。如果出现异常头部位置或斜视等重大变化,未来可考虑手术干预。该病例强调了对先天性眼球运动障碍进行仔细评估的必要性,以避免误诊并确保适当的管理。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/c8b1/11680492/0f7783c8aef6/cureus-0016-00000074460-i01.jpg

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