Mehel E, Quére M A, Lavenant F, Pechereau A
Clinique ophtalmologique, Hŏtel-Dieu, CHU, Nantes.
J Fr Ophtalmol. 1996;19(8-9):533-42.
In a retrospective study on 155 patients with Stilling-Turk-Duane's syndrome, we compare our results with those described in the literature. Particular focus was based on the different clinical entities observed.
Patients were selected from 8000 charts of cases of strabismus seen in the Ophthalmological Clinic of the CHU in Nantes between 1980 and 1995. An oculomotor assessment carried out for all of these patients allowed us to determine the clinical type according to Malbran's classification. Patients were classified on the basis of family history of oculomotor disorder and associated pathology.
The incidence of this syndrome in the population of strabismic patients was 1.9%. The number of women affected was 83 (53.5%). The syndrome was unilateral in 121 cases (78.1%). The left eye (71.9%) was affected more frequently than the right. Clinical entities not described by Malbran's classification were found in 24% of cases. These were described and classified. The oculomotor disorder most frequently encountered was esotropia. The number of patients with a amblyopia was 51 cases (32.9%). The number of patients with a torticollis was 101 cases (65.1%). The number of cases with associated medical pathology was 38 (24.5%). This pathology was ocular in 17 cases (10,9%) and extra-ocular in 22 cases (14.2%). The number of patients with a family history of oculomotor disorder was 39 (22.2%) among which 9 (5.8%) had at least one family member with Stilling-Turk-Duane's syndrome.
Data provided by this study allowed us to analyse the clinical and epidemiological features of the Stilling-Turk-Duane's syndrome. What is more, they allowed us to describe and classify clinical forms not described by Malbran's classification.
在一项针对155例斯蒂林-图尔克-杜安综合征患者的回顾性研究中，我们将我们的结果与文献中描述的结果进行了比较。特别关注的是观察到的不同临床类型。
从1980年至1995年在南特大学中心医院眼科诊所所见的8000例斜视病例图表中选取患者。对所有这些患者进行的动眼神经评估使我们能够根据马尔布兰分类法确定临床类型。患者根据动眼神经障碍家族史和相关病理进行分类。
该综合征在斜视患者人群中的发病率为1.9%。受影响的女性人数为83人（53.5%）。该综合征在121例（78.1%）中为单侧性。左眼（71.9%）比右眼更常受累。24%的病例中发现了马尔布兰分类法未描述的临床类型。对这些类型进行了描述和分类。最常遇到的动眼神经障碍是内斜视。弱视患者人数为51例（32.9%）。斜颈患者人数为101例（65.1%）。伴有相关内科病理的病例数为38例（24.5%）。这种病理在17例（10.9%）中为眼部病变，在22例（14.2%）中为眼外病变。有动眼神经障碍家族史的患者人数为39例（22.2%），其中9例（5.8%）至少有一名家庭成员患有斯蒂林-图尔克-杜安综合征。
本研究提供的数据使我们能够分析斯蒂林-图尔克-杜安综合征的临床和流行病学特征。此外，还使我们能够描述和分类马尔布兰分类法未描述的临床类型。
