Giridharan Selvaraj
Oncology, Tawam Hospital, Al Ain, ARE.
Cureus. 2024 Nov 27;16(11):e74552. doi: 10.7759/cureus.74552. eCollection 2024 Nov.
Telomeres, which protect the chromosomal ends, are vital for cellular senescence and health. Telomere shortening, often due to stress, inflammation, and oxidative damage, is linked to age-related diseases such as cancer, cardiovascular issues, and neurodegeneration. Evidence suggests that meditation may affect telomere dynamics by reducing stress and inflammation and improving emotional regulation. Clinical trials have demonstrated that the effectiveness of these practices in increasing telomerase activity and maintaining telomere length varies by type, intensity, and duration of the practice. Yoga and meditation boost cellular resilience by lowering stress, inflammation, and oxidative damage and enhancing neuroendocrine regulation. Despite promising results, study design variability and limited long-term data require further research. Future studies should identify the most effective components, dose-response relationships, and long-term effects across populations. Increasing evidence suggests that yoga and meditation could be key preventive and therapeutic strategies to improve cellular health and longevity.
端粒可保护染色体末端，对细胞衰老和健康至关重要。端粒缩短通常是由压力、炎症和氧化损伤引起的，与癌症、心血管问题和神经退行性变等与年龄相关的疾病有关。有证据表明，冥想可能通过减轻压力和炎症以及改善情绪调节来影响端粒动态。临床试验表明，这些练习在增加端粒酶活性和维持端粒长度方面的有效性因练习的类型、强度和持续时间而异。瑜伽和冥想通过减轻压力、炎症和氧化损伤以及增强神经内分泌调节来提高细胞弹性。尽管取得了令人鼓舞的结果，但研究设计的可变性和有限的长期数据仍需要进一步研究。未来的研究应确定最有效的成分、剂量反应关系以及不同人群的长期影响。越来越多的证据表明，瑜伽和冥想可能是改善细胞健康和长寿的关键预防和治疗策略。
