Singh Gurpremjit J, Kumar Deepak, Mittal Ankur, Panwar Vikas, Agarwal Harshit
Surgical Disciplines, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Urology, All India Institute of Medical Sciences, Rishikesh, Rishikesh, IND.
Cureus. 2024 Nov 29;16(11):e74759. doi: 10.7759/cureus.74759. eCollection 2024 Nov.
The initial six months following HIV infection have a high viral load. Nonspecific presentations might lead to the missing primary HIV diagnosis. Multiorgan and multisystem diagnosis is a rare presentation of primary HIV. A 40-year-old male patient with no documented comorbidities presented with bilateral flank pain. The onset of the pain was gradual, characterized as dull and aching, with radiation toward the groin. The patient also had severe pain in the left shoulder and left ankle region. Per-abdominal examination revealed bilateral flank tenderness, with the right side being more tender than the left. Swelling of the left shoulder and ankle was observed, accompanied by tenderness and a restricted range of motion. Contrast-enhanced computed tomography of the chest and abdomen revealed bilateral pyelonephritis multiple renal abscesses and liver abscesses. Left shoulder septic arthritis was also present. Pus culture and blood culture were positive for methicillin-sensitive . Antibiotics, according to the culture sensitivity, were given, and retroviral therapy was started from the antiretroviral clinic. Primary HIV infection can present with a variety of signs and symptoms. This case demonstrates that AIDS can affect any organ and mimic other disease processes. The initial clinical picture might be confused with individually occurring diseases; therefore, we should consider AIDS in patients presenting with multiorgan failure. Early initiation of empiric and then culture-specific antibiotics along with antiretroviral therapy helps in the rapid improvement of the patient and controls the high viremia. The infected patient also needs appropriate counseling on ways to avoid high-risk behavior, which may prevent transmission of HIV.
HIV感染后的最初六个月病毒载量很高。非特异性表现可能导致原发性HIV诊断漏诊。多器官和多系统诊断是原发性HIV的罕见表现。一名40岁男性患者,无合并症记录,出现双侧胁腹疼痛。疼痛逐渐发作,表现为钝痛和隐痛,向腹股沟放射。患者左肩部和左脚踝区域也有剧痛。腹部检查发现双侧胁腹压痛,右侧比左侧更压痛。观察到左肩部和脚踝肿胀,伴有压痛和活动范围受限。胸部和腹部增强CT显示双侧肾盂肾炎、多发肾脓肿和肝脓肿。还存在左肩化脓性关节炎。脓液培养和血培养对甲氧西林敏感菌呈阳性。根据培养敏感性给予抗生素,并从抗逆转录病毒诊所开始抗逆转录病毒治疗。原发性HIV感染可表现出多种体征和症状。该病例表明,艾滋病可影响任何器官并模仿其他疾病过程。最初的临床表现可能与个别疾病混淆;因此,对于出现多器官功能衰竭的患者,我们应考虑艾滋病。早期开始经验性治疗,然后使用针对培养结果的抗生素以及抗逆转录病毒治疗,有助于患者迅速康复并控制高病毒血症。感染患者还需要接受关于避免高危行为方式的适当咨询,这可能预防HIV传播。