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补阳益胃汤调节胃癌肠道菌群的研究进展

Research Progress of Buyang Yiwei Decoction in Regulating Intestinal Flora for Gastric Cancer.

作者信息

Li Yu, Wang Manya, Zhao Huixie

机构信息

Oncology Department, The First Affiliated Hospital of Heilongjiang University of Traditional Chinese Medicine, Harbin, People's Republic of China.

Department of Traditional Chinese Medicine, Shanghai Pudong New Area Nanhui Xincheng Community Health Service Center, Pudong New Area, Shanghai, People's Republic of China.

出版信息

Cancer Manag Res. 2024 Dec 23;16:1863-1869. doi: 10.2147/CMAR.S496404. eCollection 2024.

DOI:10.2147/CMAR.S496404
PMID:39735255
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11675287/
Abstract

Intestinal flora is a complex micro-ecosystem in human body, which is called the second genome of human body. Intestinal flora imbalance plays an important role in the occurrence and development of gastric cancer through circulation, metabolism and immunity. Gastric cancer is associated with dysbacteriosis. Traditional Chinese medicine (TCM) compounds in Buyang Yiwei Decoction can reduce the clinical signs and symptoms of gastric cancer by regulating intestinal microbiota, alleviate the adverse reactions of gastric cancer after radiotherapy and chemotherapy, and improve the quality of life of patients. This article reviews whether Buyang Yiwei Decoction can reduce the risk of gastric cancer or play a therapeutic role in gastric cancer by improving the intestinal microbiota.

摘要

肠道菌群是人体中一个复杂的微生态系统,被称为人体的第二基因组。肠道菌群失衡通过循环、代谢和免疫在胃癌的发生发展中起重要作用。胃癌与菌群失调有关。补阳益胃汤中的中药复方可通过调节肠道微生物群来减轻胃癌的临床症状和体征,缓解胃癌放化疗后的不良反应,提高患者生活质量。本文综述补阳益胃汤是否能通过改善肠道微生物群降低胃癌风险或在胃癌中发挥治疗作用。