胃肠道癌症与抑郁症之间的双向关系：关键在于微生物群-肠道-脑轴。
Bidirectional relationship between gastrointestinal cancer and depression: The key is in the microbiota-gut-brain axis.
作者信息
Priego-Parra Bryan Adrian, Remes-Troche Jose Maria
机构信息
Digestive Physiology and Gastrointestinal Motility Laboratory, Instituto de Investigaciones Médico-Biológicas, Universidad Veracruzana, Veracruz 91700, Mexico.
出版信息
World J Gastroenterol. 2024 Dec 28;30(48):5104-5110. doi: 10.3748/wjg.v30.i48.5104.
Abstract
In this Editorial, we review the recent publication in the , which explores the complex relationship between depression and gastric cancer and offers perspectives. Key topics discussed include the microbiota-gut-brain axis, dysbiosis, and the influence of microbial metabolites in homeostasis. Additionally, we address toxic stress caused by hypothalamic-pituitary-adrenal axis dysregulation, psychological assessments, and future research directions. Our Editorial aims to expand the understanding of the bidirectional relationship between depression and gastrointestinal cancer.
摘要
在这篇社论中，我们回顾了近期发表在[期刊名称未给出]上的一篇文章，该文章探讨了抑郁症与胃癌之间的复杂关系并提供了相关观点。讨论的关键主题包括微生物群 - 肠 - 脑轴、生态失调以及微生物代谢产物对体内平衡的影响。此外，我们还阐述了下丘脑 - 垂体 - 肾上腺轴失调引起的毒性应激、心理评估以及未来的研究方向。我们的社论旨在扩展对抑郁症与胃肠道癌症之间双向关系的理解。
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