Center for Weight, Eating, and Lifestyle Science, Drexel University, 3201 Chestnut Street, Philadelphia, PA, 19104, United States.
Center for Weight and Eating Disorders, Department of Psychiatry, Perelman School of Medicine, University of Pennsylvania, 3535 Market Street, Philadelphia, PA, 19104, United States.
Curr Obes Rep. 2024 Jun;13(2):214-223. doi: 10.1007/s13679-024-00569-w. Epub 2024 May 18.
Detail recent advancements in the science on ultra-processed food (UPF) addiction, focusing on estimated prevalence rates and emerging health disparities; progress towards identifying biological underpinnings and behavioral mechanisms; and implications for weight management.
Notable developments in the field have included: (1) estimating the global prevalence of UPF addiction at 14% of adults and 15% of youths; (2) revealing health disparities for persons of color and those with food insecurity; (3) observing altered functioning across the brain-gut-microbiome axis; (4) providing early evidence for UPF withdrawal; and (5) elucidating poorer weight management outcomes among persons with UPF addiction. The breadth of recent work on UPF addiction illustrates continued scientific and public interest in the construct and its implications for understanding and treating overeating behaviors and obesity. One pressing gap is the lack of targeted interventions for UPF addiction, which may result in more optimal clinical outcomes for this underserved population.
综述目的:详述超加工食品(UPF)成瘾相关科学的最新进展,重点关注预估流行率和新出现的健康差异;探索生物基础和行为机制的进展;以及对体重管理的影响。
最新发现:该领域的显著进展包括:(1)估计全球有 14%的成年人和 15%的青少年对 UPF 上瘾;(2)揭示了不同种族和食物无保障人群的健康差异;(3)观察到大脑-肠道-微生物组轴的功能改变;(4)提供了 UPF 戒断的早期证据;(5)阐明了 UPF 成瘾者体重管理较差的后果。最近关于 UPF 成瘾的广泛研究表明,科学界和公众对该概念及其对理解和治疗暴饮暴食行为和肥胖的影响仍保持持续关注。目前亟待解决的一个问题是缺乏针对 UPF 成瘾的干预措施,这可能会为这一服务不足的人群带来更理想的临床效果。