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缅甸大米中的总砷和无机砷。

Total arsenic and inorganic arsenic in Myanmar rice.

作者信息

Alrashdi May M, Strashnov Ilya, Richards Laura A, Tun Yin Min, Al Bualy Ahmed, Polya David A

机构信息

Department of Chemistry, School of Natural Sciences, Faculty of Science and Engineering, The University of Manchester, Manchester, M13 9PL, United Kingdom.

Chemistry Department, College of Science, Jouf University, P.O. Box: 2014, Sakaka, Kingdom of Saudi Arabia.

出版信息

Heliyon. 2024 Dec 5;10(24):e40987. doi: 10.1016/j.heliyon.2024.e40987. eCollection 2024 Dec 30.

Abstract

Myanmar is a major rice exporter. Rice is an important source of nourishment for its population. However, rice can be contaminated with toxic elements, including arsenic, long-term exposure to which has been linked to several illnesses, including cancer. There is a paucity of published data on arsenic in Myanmar rice. This study analysed rice (n = 50) from southern, middle and northern Myanmar for both total arsenic (T-As) (by ICP-MS) and inorganic arsenic (i-As) (by species-specific hydride generation ICP-MS or HPLC-ICP-MS). The mean concentration of T-As was 110 μg kg(IQR 75-142 μg kg), of which 86 μg kg (IQR 58-113 μg kg) was high toxicity i-As. The calculated mean i-As intake arising from typical consumption of this rice normalised to typical body weights in Myanmar was approximately 1 μg.kg-bw.day, close to the recently withdrawn WHO, PTWI of 2.1 μg.kg-bw.dayand higher than the EFSA reported BMDL for skin cancers of 0.06 μg.kg-bw.day.

摘要

缅甸是主要的大米出口国。大米是该国人口重要的营养来源。然而,大米可能会被有毒元素污染,包括砷,长期接触砷与多种疾病有关,包括癌症。关于缅甸大米中砷含量的已发表数据很少。本研究分析了来自缅甸南部、中部和北部的大米(n = 50)中的总砷(通过电感耦合等离子体质谱法测定)和无机砷(通过特定物种氢化物发生电感耦合等离子体质谱法或高效液相色谱 - 电感耦合等离子体质谱法测定)。总砷的平均浓度为110μg/kg(四分位间距75 - 142μg/kg),其中86μg/kg(四分位间距58 - 113μg/kg)是高毒性无机砷。根据缅甸的典型体重,这种大米的典型消费量计算得出的无机砷平均摄入量约为1μg·kg体重·天,接近世界卫生组织最近撤销的2.1μg·kg体重·天的暂定每周耐受摄入量,且高于欧洲食品安全局报告的皮肤癌基准剂量下限0.06μg·kg体重·天。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9b88/11681864/1ad9b3eda1f2/ga1.jpg

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