Alrashdi May M, Strashnov Ilya, Richards Laura A, Tun Yin Min, Al Bualy Ahmed, Polya David A
Department of Chemistry, School of Natural Sciences, Faculty of Science and Engineering, The University of Manchester, Manchester, M13 9PL, United Kingdom.
Chemistry Department, College of Science, Jouf University, P.O. Box: 2014, Sakaka, Kingdom of Saudi Arabia.
Heliyon. 2024 Dec 5;10(24):e40987. doi: 10.1016/j.heliyon.2024.e40987. eCollection 2024 Dec 30.
Myanmar is a major rice exporter. Rice is an important source of nourishment for its population. However, rice can be contaminated with toxic elements, including arsenic, long-term exposure to which has been linked to several illnesses, including cancer. There is a paucity of published data on arsenic in Myanmar rice. This study analysed rice (n = 50) from southern, middle and northern Myanmar for both total arsenic (T-As) (by ICP-MS) and inorganic arsenic (i-As) (by species-specific hydride generation ICP-MS or HPLC-ICP-MS). The mean concentration of T-As was 110 μg kg(IQR 75-142 μg kg), of which 86 μg kg (IQR 58-113 μg kg) was high toxicity i-As. The calculated mean i-As intake arising from typical consumption of this rice normalised to typical body weights in Myanmar was approximately 1 μg.kg-bw.day, close to the recently withdrawn WHO, PTWI of 2.1 μg.kg-bw.dayand higher than the EFSA reported BMDL for skin cancers of 0.06 μg.kg-bw.day.
缅甸是主要的大米出口国。大米是该国人口重要的营养来源。然而,大米可能会被有毒元素污染,包括砷,长期接触砷与多种疾病有关,包括癌症。关于缅甸大米中砷含量的已发表数据很少。本研究分析了来自缅甸南部、中部和北部的大米(n = 50)中的总砷(通过电感耦合等离子体质谱法测定)和无机砷(通过特定物种氢化物发生电感耦合等离子体质谱法或高效液相色谱 - 电感耦合等离子体质谱法测定)。总砷的平均浓度为110μg/kg(四分位间距75 - 142μg/kg),其中86μg/kg(四分位间距58 - 113μg/kg)是高毒性无机砷。根据缅甸的典型体重,这种大米的典型消费量计算得出的无机砷平均摄入量约为1μg·kg体重·天,接近世界卫生组织最近撤销的2.1μg·kg体重·天的暂定每周耐受摄入量,且高于欧洲食品安全局报告的皮肤癌基准剂量下限0.06μg·kg体重·天。