Zhang Cuiwen, Liu Linlin, Jiang Yiping
The First Clinical Medical College of Gannan Medical University, Ganzhou, China.
First Affiliated Hospital of Gannan Medical University, Ganzhou, China.
Front Med (Lausanne). 2024 Dec 13;11:1492828. doi: 10.3389/fmed.2024.1492828. eCollection 2024.
To observe the changes in peripapillary retinal nerve fiber layer (RNFL) thickness and peripapillary vessel densities (VD) in patients with rhegmatogenous retinal detachment (RRD) after scleral buckling (SB) by OCTA.
A total of 40 patients (40 eyes) with monocular RRD who underwent SB were included in the study, with the operated eyes (40 eyes) as the study group and the contralateral healthy eyes (40 eyes) as the control to analyse the changes in peripapillary RNFL thickness and VD before and after surgery. Data were analysed by paired samples -test or Wilcoxon signed rank sum test.
Comparison of the peripapillary RNFL thickness in the 8 areas between the two groups during the 6-month follow-up period: All 8 peripapillary areas of the optic disc were statistically different before surgery, except for the tempo superior and tempo inferior, which were statistically different at each postoperative follow-up point, and the remaining 6 areas in the operated eyes group were progressively closer to those in the healthy eyes group, and there was no significant difference between the two groups. Comparison of peripapillary VD in the 8 areas between the two groups during the 6-month follow-up: Peripapillary VD in the 8 areas in the two groups were all statistically different before surgery, and except for superior tempo, which was statistically different at each postoperative follow-up time point, the remaining seven areas in the operated eyes group became progressively closer to that in the healthy eyes group and there was no significant difference.
RRD negatively affects the peripapillary RNFL, but both peripapillary RNFL thickness and VD gradually improved in the operated eyes close to the contralateral eyes after SB.
通过光学相干断层扫描血管造影（OCTA）观察孔源性视网膜脱离（RRD）患者巩膜扣带术（SB）后视乳头周围视网膜神经纤维层（RNFL）厚度和视乳头周围血管密度（VD）的变化。
本研究纳入40例接受SB的单眼RRD患者（40只眼），将手术眼（40只眼）作为研究组，对侧健康眼（40只眼）作为对照组，分析手术前后视乳头周围RNFL厚度和VD的变化。数据采用配对样本t检验或Wilcoxon符号秩和检验进行分析。
6个月随访期间两组8个区域视乳头周围RNFL厚度比较：术前视盘的所有8个视乳头周围区域差异均有统计学意义，除颞上和颞下区域外，术后各随访时间点差异均有统计学意义，手术眼组其余6个区域逐渐接近健康眼组，两组间差异无统计学意义。6个月随访期间两组8个区域视乳头周围VD比较：术前两组8个区域视乳头周围VD差异均有统计学意义，除颞上区域术后各随访时间点差异有统计学意义外，手术眼组其余7个区域逐渐接近健康眼组，差异无统计学意义。
RRD对视乳头周围RNFL有负面影响，但SB术后手术眼视乳头周围RNFL厚度和VD均逐渐改善，接近对侧眼。
