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38岁未育女性的卵巢胎儿型畸胎瘤:一例报告

Ovarian Fetiform Teratoma in 38 Years Nulliparous Woman: A Case Report.

作者信息

Gedamu Desalew, Wondafrash Mekitie, Berhanu Meron

机构信息

Department of Pathology St Paul's Hospital Millennium Medical College Addis Ababa Ethiopia.

St. Paul's Institute for Reproductive Health and Rights Addis Ababa Ethiopia.

出版信息

Clin Case Rep. 2024 Dec 25;13(1):e70029. doi: 10.1002/ccr3.70029. eCollection 2025 Jan.

DOI:10.1002/ccr3.70029
PMID:39735795
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11669493/
Abstract

Fetiform teratoma, another name for homunculus, is a rare form of mature teratoma that is highly differentiated and has parts that resemble a malformed fetus. We reported a case of ovarian Fetiform teratoma in a 38 years old nulliparous woman presented with right side abdominal distention of 10 years duration. An ultrasound revealed a heterogeneous pelvic cystic mass that ranged in appearance from fully hyperechoic to fully hypoechoic, suggesting mature cystic teratoma. The patient underwent laparotomy. Histopathology of Cystectomy specimen was found to be compatible with Fetiform teratoma. It is important to distinguish this highly differentiated benign neoplasm with potential somatic malignant transformation from Fetus in fetu and ectopic pregnancy. To establish the diagnosis, a thorough clinicopathologic examination, laboratory tests for pregnancy and relevant cytogenetic tests for Zygosity should be performed.

摘要

胎儿样畸胎瘤,又称小人儿,是成熟畸胎瘤的一种罕见形式,高度分化,有类似畸形胎儿的部分。我们报告了一例38岁未生育女性的卵巢胎儿样畸胎瘤病例,该患者右侧腹部膨隆10年。超声检查发现盆腔有一个不均匀的囊性肿块,外观从完全高回声到完全低回声不等,提示为成熟囊性畸胎瘤。患者接受了剖腹手术。囊肿切除标本的组织病理学检查结果与胎儿样畸胎瘤相符。将这种具有潜在体细胞恶性转化的高度分化良性肿瘤与胎中胎和异位妊娠区分开来很重要。为明确诊断,应进行全面的临床病理检查、妊娠实验室检查以及相关的合子性细胞遗传学检查。

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引用本文的文献

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Fetiform teratoma: a systematic review with insights into concepts and controversies in differentiating it from fetus-in-fetu.胎儿样畸胎瘤:一项系统综述,深入探讨将其与胎内胎相鉴别的概念及争议
Pediatr Surg Int. 2025 Jun 14;41(1):170. doi: 10.1007/s00383-025-06087-7.

本文引用的文献

1
Fetus in fetu in an adult woman.成年女性体内的胎中胎。
BMJ Case Rep. 2019 Aug 12;12(8):e230835. doi: 10.1136/bcr-2019-230835.
2
[Homunculus: Fetiform teratoma].[侏儒畸胎瘤:胎儿形畸胎瘤]
Gynecol Obstet Fertil. 2012 Feb;40(2):121-3. doi: 10.1016/j.gyobfe.2011.07.046. Epub 2012 Jan 26.
3
Ovarian mature cystic teratoma containing homunculus: a case report.卵巢成熟囊性畸胎瘤内含小人儿:一例报告
J Korean Med Sci. 2003 Dec;18(6):905-7. doi: 10.3346/jkms.2003.18.6.905.