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经皮交叉穿刺椎体成形术治疗Genant 0-1级骨质疏松性椎体压缩骨折的疗效

Efficacy of Percutaneous Vertebroplasty Using Cross-Puncture in the Treatment of Genant Grade 0-1 Osteoporotic Vertebral Compression Fractures.

作者信息

Hao Guobing, Han Zhenchuan, Zhang Nan, Liu Kun, Song Diyu, Zhang Shuming, Qiao Lin, Zhu Zexing

机构信息

Department of Orthopaedics, PLA Rocket Force Characteristic Medical Center, Beijing, China.

Department of Orthopaedics, PLA Rocket Force Characteristic Medical Center, Beijing, China.

出版信息

World Neurosurg. 2025 Mar;195:123633. doi: 10.1016/j.wneu.2024.123633. Epub 2025 Feb 11.

Abstract

BACKGROUND

Percutaneous vertebroplasty (PVP) is a common surgical method for osteoporotic vertebral compression fractures (OVCFs). The puncture method and location of the puncture needle can directly affect bone cement distribution in the vertebra. This retrospective study aimed to compare the clinical efficacy and safety of PVP using the cross-puncture and bilateral conventional puncture for the treatment of Genant grade 0-1 OVCFs.

METHODS

We retrospectively analyzed 98 patients who underwent PVP in our department between January 2019 and April 2023, including 50 and 48 treated with the cross-puncture (group A) and bilateral conventional puncture (group B), respectively. Operation time (minutes), bone cement injection volume (mL), bone cement leakage rate, bone cement classification, and related complications were compared between the groups. The visual analog scale, Oswestry Disability Index, heights of the anterior and midline of the injured vertebrae, and Cobb angle were compared preoperatively and at the follow-up. Excellent and good operation rates were evaluated using the modified Macnab criteria.

RESULTS

The bone cement leakage rate in group B (25%) was higher than that in group A (8%) (P < 0.05). However, the injection amount of bone cement in group A (5.47 ± 0.72 mL) was significantly higher than that in group B (4.43 ± 0.64 mL) (P < 0.001). The bone cement distribution grades in group A (40 cases of grade 3) were significantly better than those in group B (0 cases of grade 3) (P < 0.001). Compared with preoperative values, the visual analog scale and Oswestry Disability Index scores at each follow-up significantly decreased, anterior and midline heights of the injured vertebrae significantly increased, and Cobb angle significantly decreased in both groups (P < 0.001). The complication rate in group A (0%) was significantly lower than that in group B (10.42%) (P < 0.05). According to the modified Macnab standard, the excellent and good ratings in group A (96%) were significantly higher than those in group B (62.5%) (P < 0.001).

CONCLUSIONS

Cross-puncture and bilateral conventional puncture were both effective methods for the treatment of Genant grade 0-1 OVCFs. However, the cross-puncture was more advantageous in terms of the bone cement leakage rate, amount of bone cement injected, bone cement distribution grade, and complications.

摘要

背景

经皮椎体成形术(PVP)是治疗骨质疏松性椎体压缩骨折(OVCFs)的一种常见手术方法。穿刺方法和穿刺针的位置可直接影响椎体中骨水泥的分布。本回顾性研究旨在比较采用交叉穿刺和双侧传统穿刺的PVP治疗Genant 0-1级OVCFs的临床疗效和安全性。

方法

我们回顾性分析了2019年1月至2023年4月在我科接受PVP治疗的98例患者资料,其中分别有50例和48例接受交叉穿刺(A组)和双侧传统穿刺(B组)治疗。比较两组的手术时间(分钟)、骨水泥注入量(毫升)、骨水泥渗漏率、骨水泥分级及相关并发症。比较术前及随访时两组的视觉模拟评分、Oswestry功能障碍指数、伤椎前缘和中线高度以及Cobb角。采用改良Macnab标准评估优良手术率。

结果

B组骨水泥渗漏率(25%)高于A组(8%)(P<0.05)。然而,A组骨水泥注入量(5.47±0.72毫升)显著高于B组(4.43±0.64毫升)(P<0.001)。A组骨水泥分布分级(3级40例)明显优于B组(3级0例)(P<0.001)。与术前值相比,两组各随访时的视觉模拟评分和Oswestry功能障碍指数评分均显著降低,伤椎前缘和中线高度显著增加,Cobb角显著减小(P<0.001)。A组并发症发生率(0%)显著低于B组(10.42%)(P<0.05)。根据改良Macnab标准,A组优良率(96%)显著高于B组(62.5%)(P<0.001)。

结论

交叉穿刺和双侧传统穿刺都是治疗Genant 0-1级OVCFs的有效方法。然而,交叉穿刺在骨水泥渗漏率、骨水泥注入量、骨水泥分布分级及并发症方面更具优势。

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