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自体颅骨成形术后骨碎片吸收导致的延迟性和复发性手术部位感染:一例报告

Delayed and recurrent surgical site infection from resorbed bone fragment after autologous cranioplasty: a case report.

作者信息

Seok Jin Hoo, Roh Hae Won, Kim Jong Hyun

机构信息

Department of Neurosurgery, Korea University Guro Hospital, Korea University College of Medicine, Seoul, Korea.

出版信息

J Trauma Inj. 2024 Dec;37(4):304-308. doi: 10.20408/jti.2024.0052. Epub 2024 Dec 16.

DOI:10.20408/jti.2024.0052
PMID:39736505
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11703701/
Abstract

Decompressive craniectomy is one of the most common procedures for managing severe traumatic brain injury. Cranioplasty plays a vital role in restoring the integrity of the skull and preventing complications that may arise after a decompressive craniectomy. This case report presents a 24-year-old woman who underwent cranioplasty with a cryopreserved autologous bone flap. Initially successful, the procedure was later complicated by a delayed surgical site infection and methicillin-resistant Staphylococcus aureus osteomyelitis, ultimately resulting in complete resorption of the bone flap. The report discusses the consequences of autologous bone flap resorption and surgical site infection, highlighting the critical need for effective sterilization and proper bone storage techniques. This case emphasizes the necessity of exploring alternative strategies to improve cranioplasty outcomes and minimize the risk of infection.

摘要

去骨瓣减压术是治疗重度创伤性脑损伤最常见的手术之一。颅骨修补术在恢复颅骨完整性及预防去骨瓣减压术后可能出现的并发症方面起着至关重要的作用。本病例报告介绍了一名24岁女性,她接受了使用低温保存的自体骨瓣进行颅骨修补术。该手术最初成功,但后来出现了手术部位延迟感染和耐甲氧西林金黄色葡萄球菌骨髓炎的并发症,最终导致骨瓣完全吸收。该报告讨论了自体骨瓣吸收和手术部位感染的后果,强调了有效消毒和适当骨储存技术的迫切需求。本病例强调了探索替代策略以改善颅骨修补术结果并将感染风险降至最低的必要性。

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本文引用的文献

1
Bone flap management strategies for postcraniotomy surgical site infection.开颅术后手术部位感染的骨瓣处理策略
Surg Neurol Int. 2021 Jul 12;12:341. doi: 10.25259/SNI_276_2021. eCollection 2021.
2
Cranial bone flap resorption-pathological features and their implications for clinical treatment.颅骨骨瓣吸收的病理特征及其对临床治疗的影响。
Neurosurg Rev. 2021 Aug;44(4):2253-2260. doi: 10.1007/s10143-020-01417-w. Epub 2020 Oct 12.
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Timing of cranial reconstruction after cranioplasty infections: are we ready for a re-thinking? A comparative analysis of delayed versus immediate cranioplasty after debridement in a series of 48 patients.
颅骨修补术后感染后行颅骨重建的时机:我们是否需要重新思考?在一系列 48 例清创术后延迟与即刻颅骨修补的对比分析。
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PLoS One. 2020 Jan 30;15(1):e0228009. doi: 10.1371/journal.pone.0228009. eCollection 2020.
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World Neurosurg. 2018 Jul;115:e111-e118. doi: 10.1016/j.wneu.2018.03.197. Epub 2018 Apr 4.
6
Cryostored autologous skull bone for cranioplasty? A study on cranial bone flaps' viability and microbial contamination after deep-frozen storage at -80°C.用于颅骨成形术的低温保存自体颅骨?关于颅骨瓣在-80°C深度冷冻保存后的活力和微生物污染的研究。
J Clin Neurosci. 2017 Aug;42:81-83. doi: 10.1016/j.jocn.2017.04.016. Epub 2017 Apr 18.
7
Complications After In Vivo and Ex Vivo Autologous Bone Flap Storage for Cranioplasty: A Comparative Analysis of the Literature.颅骨成形术中体内和体外自体骨瓣储存后的并发症:文献比较分析
World Neurosurg. 2016 Dec;96:510-515. doi: 10.1016/j.wneu.2016.09.025. Epub 2016 Sep 16.
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Resorption of Autogenous Bone Graft in Cranioplasty: Resorption and Reintegration Failure.颅骨成形术中自体骨移植的吸收:吸收与再整合失败。
Korean J Neurotrauma. 2014 Apr;10(1):10-4. doi: 10.13004/kjnt.2014.10.1.10. Epub 2014 Apr 30.
9
Cryopreservation versus subcutaneous preservation of autologous bone flaps for cranioplasty: comparison of the surgical site infection and bone resorption rates.自体骨瓣用于颅骨成形术的冷冻保存与皮下保存:手术部位感染率和骨吸收率的比较
Clin Neurol Neurosurg. 2014 Sep;124:85-9. doi: 10.1016/j.clineuro.2014.06.029. Epub 2014 Jul 1.
10
Bone flap resorption: risk factors for the development of a long-term complication following cranioplasty after decompressive craniectomy.骨瓣吸收:去骨瓣减压术后颅骨修补长期并发症的发展风险因素。
J Neurotrauma. 2013 Jan 15;30(2):91-5. doi: 10.1089/neu.2012.2542.