Massimo C, Orazio A, Felice F
J Neurosurg. 1985 Apr;62(4):532-8. doi: 10.3171/jns.1985.62.4.0532.
Postoperative morbidity in patients with intracranial stenotic lesions following extracranial-intracranial arterial (EC-IC) bypass is not well defined. A high rate of neurological complications associated with occlusion of the stenotic arteries after surgery has recently been reported. In the period June, 1976, to March, 1984, the authors performed EC-IC bypass procedures in 19 patients with intracranial stenotic arteries. Most of the patients were initially treated pharmacologically (usually by anticoagulant therapy). Surgery was performed if the symptoms recurred while the patients were under pharmacological treatment and if angiography confirmed arterial stenosis. Antiplatelet therapy was given until the day of surgery and during the entire follow-up period. No permanent postoperative morbidity was observed in the series. One patient, with stenosis of the left siphon, the A1 segment of the anterior cerebral artery, and the M1 segment of the middle cerebral artery, had a transient dysphasia and right hemiparesis (lasting 3 days) in the presence of an unchanged arterial stenosis. In five patients early postoperative angiography (at 5 to 21 days) revealed occlusion of previously stenotic arteries. In one patient the occlusion was disclosed only on a later angiographic study, 2 months after surgery. Although EC-IC bypass is generally not a very high-risk operation in patients with intracranial arterial stenosis, there is a high percentage of immediate postoperative occlusion, and the authors suggest caution in determining indication for surgical treatment.
颅外-颅内动脉(EC-IC)搭桥术后颅内狭窄性病变患者的术后发病率尚不明确。最近有报道称,手术后与狭窄动脉闭塞相关的神经并发症发生率很高。在1976年6月至1984年3月期间,作者对19例颅内狭窄动脉患者进行了EC-IC搭桥手术。大多数患者最初接受药物治疗(通常采用抗凝治疗)。如果患者在药物治疗期间症状复发且血管造影证实动脉狭窄,则进行手术。术前及整个随访期间均给予抗血小板治疗。该系列中未观察到永久性术后发病率。一名患者,其左侧虹吸部、大脑前动脉A1段和大脑中动脉M1段狭窄,在动脉狭窄无变化的情况下出现短暂性失语和右侧偏瘫(持续3天)。5例患者术后早期血管造影(术后5至21天)显示先前狭窄的动脉闭塞。1例患者仅在术后2个月的后续血管造影研究中发现闭塞。尽管EC-IC搭桥术对于颅内动脉狭窄患者通常不是一项风险很高的手术,但术后即刻闭塞的比例很高,作者建议在确定手术治疗指征时应谨慎。