半腱肌肌腱在磁共振图像上的横截面积与胶原纤维直径密切相关。
Cross-sectional area on magnetic resonance images of the semitendinosus tendon is strongly related to the collagen fibril diameter.
作者信息
Mizuno Yushin, Nakase Junsuke, Ishikawa Tatsuya, Asai Kazuki, Takata Yasushi, Kanayama Tomoyuki, Sengoku Takuya, Ozaki Noriyuki, Tsuchiya Hiroyuki
机构信息
Department of Orthopaedic Surgery Graduate School of Medical Sciences Kanazawa University Kanazawa Ishikawa Japan.
Section of Rehabilitation Kanazawa University Hospital Kanazawa Ishikawa Japan.
出版信息
J Exp Orthop. 2024 Dec 30;12(1):e70124. doi: 10.1002/jeo2.70124. eCollection 2025 Jan.
PURPOSE
Using a thin semitendinosus tendon as an autograft is a risk factor for poor clinical outcomes after anterior cruciate ligament reconstruction. Preoperative evaluation of the cross-sectional area of the semitendinosus tendon using magnetic resonance imaging is useful. However, studies comparing the cross-sectional area of the semitendinosus tendon on magnetic resonance imaging and the collagen fibril diameter of the semitendinosus tendon are lacking. We aimed to investigate the relationship between collagen fibril diameter and cross-sectional area of the semitendinosus tendon using magnetic resonance imaging.
METHODS
We included 14 patients (24.5 ± 12.3 years) who underwent anterior cruciate or medial patellofemoral ligament reconstruction using the semitendinosus tendon. Samples not used to prepare autografts were used to evaluate the collagen fibril diameter. Transmission electron microscopy was used to measure several hundred short fibril diameters per sample. Magnetic resonance imaging (T2-weighted imaging) was used to assess the cross-sectional area of the semitendinosus tendon, measured 8 cm proximal to the tibial attachment. Spearman's rank correlation coefficients were determined for collagen fibril diameter and cross-sectional area of the semitendinosus tendon on magnetic resonance imaging, and the relationship between both parameters was evaluated.
RESULTS
The collagen fibril diameter of the semitendinosus tendon was calculated from 10,279 fibrils. The correlation coefficient between the collagen fibril diameter and the cross-sectional area of the semitendinosus tendon was 0.821 ( < 0.001).
CONCLUSIONS
A strong positive correlation was observed between the collagen fibril diameter and cross-sectional area of the semitendinosus tendon. A small cross-sectional area on the magnetic resonance image of the semitendinosus tendon indicated a thin collagen fibril diameter, which may affect the mechanical strength of the autograft for anterior cruciate ligament reconstruction. The collagen fibril diameter can be predicted preoperatively by measuring the cross-sectional area of the semitendinosus tendon using magnetic resonance imaging.
LEVEL OF EVIDENCE
Level IV.
目的
使用细的半腱肌腱作为自体移植物是前交叉韧带重建术后临床效果不佳的一个风险因素。术前使用磁共振成像评估半腱肌腱的横截面积很有用。然而，缺乏比较磁共振成像上半腱肌腱的横截面积与半腱肌腱胶原纤维直径的研究。我们旨在利用磁共振成像研究半腱肌腱胶原纤维直径与横截面积之间的关系。
方法
我们纳入了14例（24.5±12.3岁）使用半腱肌腱进行前交叉韧带或髌股内侧韧带重建的患者。未用于制备自体移植物的样本用于评估胶原纤维直径。使用透射电子显微镜测量每个样本数百根短纤维的直径。使用磁共振成像（T2加权成像）评估半腱肌腱的横截面积，在距胫骨附着点近端8厘米处测量。确定半腱肌腱胶原纤维直径与磁共振成像上半腱肌腱横截面积的Spearman等级相关系数，并评估这两个参数之间的关系。
结果
从10279根纤维计算出半腱肌腱的胶原纤维直径。胶原纤维直径与半腱肌腱横截面积之间的相关系数为0.821（<0.001）。
结论
观察到半腱肌腱胶原纤维直径与横截面积之间存在强正相关。半腱肌腱磁共振图像上较小的横截面积表明胶原纤维直径较细，这可能会影响前交叉韧带重建自体移植物的机械强度。通过使用磁共振成像测量半腱肌腱的横截面积，可以在术前预测胶原纤维直径。
证据水平
四级。
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