Naaman Nour, Alyafi Mohammad, Albeshri Heitham, Jamjoom Ahmed A, AlTurkistany Samira, Al-Maghrabi Haneen, Baradwan Saeed
Department of Obstetrics and Gynecology, King Faisal Specialist Hospital and Research Center, Jeddah, Saudi Arabia.
Department of Obstetrics and Gynecology, Faculty of Medicine, King Abdulaziz University, Jeddah, Saudi Arabia.
Gynecol Oncol Rep. 2024 Nov 6;56:101543. doi: 10.1016/j.gore.2024.101543. eCollection 2024 Dec.
Extrauterine recurrent metastasis of Low-grade endometrial stromal sarcoma (LG-ESS) to major blood vessels is largely rare with few reported cases.
Herein, we present a case of a 51-year-old female with recurrent LG-ESS that has metastasized after 12 years to the inferior vena cava (IVC) and extended into the right atrium and common iliac veins. Computed tomography showed an intracardiac larger thrombus within the right atrium extending into the inferior vena cava and common iliac veins. The patient underwent cytoreduction of the intravenous tumor. Final histopathology confirmed metastatic LG-ESS. Follow-up CT scan after six months showed no residual or recurrence.
Treatment for extrauterine metastasis from LG-ESS prioritizes reducing tumor burden through surgical resection and may require collaboration across disciplines. Follow-up hormonal therapy with progestins or aromatase inhibitors significantly impacts patient prognosis.
低级别子宫内膜间质肉瘤（LG-ESS）子宫外复发转移至主要血管的情况极为罕见，仅有少数病例报道。
在此，我们报告一例51岁女性复发性LG-ESS病例，该病例在12年后转移至下腔静脉（IVC），并延伸至右心房和髂总静脉。计算机断层扫描显示右心房内有一个较大的心内血栓，延伸至下腔静脉和髂总静脉。患者接受了静脉肿瘤的减瘤手术。最终组织病理学证实为转移性LG-ESS。六个月后的随访CT扫描显示无残留或复发。
LG-ESS子宫外转移的治疗优先通过手术切除减轻肿瘤负荷，可能需要多学科协作。后续使用孕激素或芳香化酶抑制剂进行激素治疗对患者预后有显著影响。
