Graziano Francis D, Plotsker Ethan L, Amakiri Uchechukwu O, Shammas Ronnie L, Vingan Perri S, Mehrara Babak J, Stern Carrie S, Nelson Jonas A, Matros Evan, Allen Robert J
From the Plastic and Reconstructive Surgery Service, Department of Surgery, Memorial Sloan Kettering Cancer Center.
Plast Reconstr Surg. 2025 Aug 1;156(2):162e-171e. doi: 10.1097/PRS.0000000000011951. Epub 2024 Dec 27.
Enhanced recovery after surgery (ERAS) protocols can reduce the length of stay (LOS) for surgical patients, including those undergoing unilateral deep inferior epigastric artery perforator (DIEP) flap breast reconstruction, allowing most patients to be discharged by postoperative day 2. However, some patients require a prolonged inpatient stay because of difficulty completing postoperative milestones. This study aims to identify factors associated with increased LOS after DIEP flap breast reconstruction and to assess safety of earlier discharge.
A retrospective review was performed of all patients who underwent unilateral DIEP flap reconstruction between January of 2021 and December of 2022 at Memorial Sloan Kettering Cancer Center. The authors assessed patient characteristics, comorbidities, and complications to identify correlations with LOS and milestone completion after implementation of an ERAS protocol.
A total of 278 patients were included; the median LOS was 2.25 days (interquartile range, 2.19 to 2.33 days). Factors associated with delayed discharge included increased age, increased operative time, history of diabetes, and history of immunologic disease. Increased operative time was the only variable associated with prolonged milestone completion. A subanalysis of the safety of an earlier discharge goal of postoperative day 1 when compared with a goal of postoperative day 2 demonstrated no significant differences in complication rates.
Discharge timing and milestone completion after unilateral DIEP flap reconstruction is variable and dependent on patient and operative characteristics. These insights can aid in patient optimization and may suggest ERAS protocol adjustments to enable earlier discharge for more patients. Furthermore, earlier discharge goals appear safe for appropriate patients.
CLINICAL QUESTION/LEVEL OF EVIDENCE: Risk, III.
术后加速康复(ERAS)方案可缩短手术患者的住院时间(LOS),包括接受单侧腹壁下深动脉穿支(DIEP)皮瓣乳房重建的患者,使大多数患者在术后第2天即可出院。然而,一些患者由于难以完成术后关键指标而需要延长住院时间。本研究旨在确定与DIEP皮瓣乳房重建后住院时间延长相关的因素,并评估早期出院的安全性。
对2021年1月至2022年12月在纪念斯隆凯特琳癌症中心接受单侧DIEP皮瓣重建的所有患者进行回顾性研究。作者评估了患者特征、合并症和并发症,以确定与实施ERAS方案后的住院时间和关键指标完成情况之间的相关性。
共纳入278例患者;中位住院时间为2.25天(四分位间距,2.19至2.33天)。与出院延迟相关的因素包括年龄增加、手术时间延长、糖尿病史和免疫疾病史。手术时间延长是与关键指标完成时间延长相关的唯一变量。与术后第2天出院目标相比,对术后第1天早期出院目标安全性的亚分析显示,并发症发生率无显著差异。
单侧DIEP皮瓣重建后的出院时间和关键指标完成情况存在差异,取决于患者和手术特征。这些见解有助于优化患者情况,并可能提示调整ERAS方案,以使更多患者能够更早出院。此外,对于合适的患者,早期出院目标似乎是安全的。
临床问题/证据水平:风险,III级。