Kim Jae-Young, Lee Chaeyeon, Park Young Long, Lee Jae-Hoon, Ryu Young Hoon, Huh Jong-Ki
Department of Oral and Maxillofacial Surgery, Yonsei University College of Dentistry, Gangnam Severance Hospital, 211 Eonju-ro, Gangnam-gu, Seoul, 06273, Republic of Korea.
Department of Oral and Maxillofacial Surgery, Bundang Cha Hospital, Seoul, Republic of Korea.
Sci Rep. 2024 Dec 30;14(1):31569. doi: 10.1038/s41598-024-71639-1.
This study aimed to investigate the cutoff values of standardized uptake values (SUVs) and their accuracy using single-photon emission computed tomography-computed tomography (SPECT-CT) for temporomandibular joint (TMJ) osteoarthritis (OA) based on magnetic resonance imaging (MRI) and clinical examination. We included 106 joints of 53 patients with TMJ OA. SUVmax and SUVpeak of each TMJ was measured. SUVref was set as the SUV at the clivus. The diagnostic performance, including sensitivity, specificity, positive predictive value (PPV), negative predictive value (NPV), and accuracy, were evaluated. SUVmax was 5.15, with a sensitivity of 59.375, specificity of 100.000, PPV of 100.000, NPV of 61.765, and accuracy of 75.472. The cutoff value for SUVpeak was 3.635, with sensitivity of 56.250, specificity of 100.000, PPV of 100.000, NPV of 60.000, and accuracy of 73.585. SUVmax was 3.286 ± 0.780 and 6.623 ± 3.442 in the non-OA and OA groups, respectively (p < 0.001). SUVpeak was 2.324 ± 0.688 and 4.913 ± 2.749 in the non-OA and OA groups, respectively (p < 0.001). SPECT-CT can be helpful for the diagnosis of patients clinically suspected of having OA. It is also recommended that clinicians keep in mind that patients with SUVmax values higher than the cutoff value should be managed with a higher possibility of OA.
本研究旨在基于磁共振成像（MRI）和临床检查，探讨使用单光子发射计算机断层扫描-计算机断层扫描（SPECT-CT）检测颞下颌关节（TMJ）骨关节炎（OA）时标准化摄取值（SUVs）的截断值及其准确性。我们纳入了53例TMJ OA患者的106个关节。测量每个TMJ的SUVmax和SUVpeak。将SUVref设定为斜坡处的SUV。评估诊断性能，包括敏感性、特异性、阳性预测值（PPV）、阴性预测值（NPV）和准确性。SUVmax为5.15，敏感性为59.375，特异性为100.000，PPV为100.000，NPV为61.765，准确性为75.472。SUVpeak的截断值为3.635，敏感性为56.250，特异性为100.000，PPV为100.000，NPV为60.000，准确性为73.585。非OA组和OA组的SUVmax分别为3.286±0.780和6.623±3.442（p<0.001）。非OA组和OA组的SUVpeak分别为2.324±0.688和4.913±2.749（p<0.001）。SPECT-CT有助于临床疑似OA患者的诊断。还建议临床医生记住，SUVmax值高于截断值的患者患OA的可能性更高，应进行相应处理。
