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对16只患有鼻腔肿块病变的犬和14只患有鼻腔肿块病变的猫进行计算机断层扫描引导下的Tru-Cut活检的回顾性评估。

Retrospective evaluation of computed tomographic-guided Tru-Cut biopsies in 16 dogs and 14 cats with nasal cavity mass lesions.

作者信息

Milne Jessica, Ekkebus Sophie, Thompson Daniel, Brash Robert

机构信息

Davies Veterinary Specialists, Part of Linnaeus Veterinary Limited, Hitchin, UK.

出版信息

J Vet Intern Med. 2025 Jan-Feb;39(1):e17296. doi: 10.1111/jvim.17296.

DOI:10.1111/jvim.17296
PMID:39739338
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC11683400/
Abstract

BACKGROUND

Approximately 80% of nasal masses in dogs and 91% of nasal masses in cats are reported to be malignant, but the currently reported diagnostic rate of neoplasia is 54% using blind or rhinoscopic biopsy techniques.

HYPOTHESIS/OBJECTIVES: Describe the technique of computed tomography (CT)-guided Tru-Cut (Tru-Cut biopsy needle, Merit Medical Systems, Utah, USA) nasal biopsies in cats and dogs to determine the diagnostic rate of neoplasia on the first round of sampling and to evaluate the safety of the technique.

ANIMALS

Thirty client-owned animals, 16 dogs and 14 cats, that had CT-guided nasal biopsies performed to investigate nasal masses.

METHODS

Retrospective, single-center, medical record review of 16 dogs and 14 cats that had CT-guided nasal biopsies performed between 2022 and 2024.

RESULTS

Diagnostic biopsy samples were acquired using CT-guided Tru-Cut sampling in 28/30 cases (93%). The diagnosis was considered clinically appropriate in 26/30 cases (87%): neoplasia in 24/30 cases (80%) and rhinitis in 2/30 cases (7%). Neoplasia was the final diagnosis in 14/16 dogs (88%) and 10/14 cats (71%).

CONCLUSIONS AND CLINICAL IMPORTANCE

Computed tomographic-guided Tru-Cut biopsies can result in a high first-round diagnosis of neoplasia in nasal masses in cats and dogs, without clinically relevant complications. This technique is a useful alternative method of sampling nasal masses that may be difficult to access via rhinoscopy.

摘要

背景

据报道,犬鼻腔肿物约80%、猫鼻腔肿物约91%为恶性,但目前采用盲法或鼻内镜活检技术报道的肿瘤诊断率为54%。

假设/目的:描述计算机断层扫描(CT)引导下对猫和犬进行Tru-Cut(Tru-Cut活检针,美国犹他州Merit Medical Systems公司)鼻腔活检的技术,以确定首轮采样时肿瘤的诊断率,并评估该技术的安全性。

动物

30只客户拥有的动物,16只犬和14只猫,接受了CT引导下的鼻腔活检以调查鼻腔肿物。

方法

对2022年至2024年间接受CT引导下鼻腔活检的16只犬和14只猫进行回顾性、单中心病历审查。

结果

28/30例(93%)采用CT引导下的Tru-Cut采样获取了诊断性活检样本。26/30例(87%)的诊断被认为在临床上是合适的:24/30例(80%)为肿瘤,2/30例(7%)为鼻炎。14/16只犬(88%)和10/14只猫(71%)最终诊断为肿瘤。

结论及临床意义

CT引导下的Tru-Cut活检可在首轮诊断中对猫和犬鼻腔肿物的肿瘤做出较高诊断率,且无临床相关并发症。该技术是一种有用的替代方法,可用于对鼻内镜难以获取样本的鼻腔肿物进行采样。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6969/11683400/b678dc9db754/JVIM-39-e17296-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6969/11683400/28d41c3365ec/JVIM-39-e17296-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6969/11683400/6ab7ea663eeb/JVIM-39-e17296-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6969/11683400/b678dc9db754/JVIM-39-e17296-g002.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6969/11683400/28d41c3365ec/JVIM-39-e17296-g003.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6969/11683400/6ab7ea663eeb/JVIM-39-e17296-g001.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/6969/11683400/b678dc9db754/JVIM-39-e17296-g002.jpg

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