Stromberg B V
J Trauma. 1985 Feb;25(2):163-4. doi: 10.1097/00005373-198502000-00015.
Presenting patient profiles and bacteriologic culture and sensitivity data from 132 patients representing a 5-year experience with hand infections were examined. Patients were subdivided into those having no prior treatment and those having previously been treated with antibiotics. Presenting patient profiles showed the majority of patients to be young to middle-aged males. Temperature, pulse, and white blood cell counts, while usually mildly elevated, were usually not diagnostic. In comparison with patients not having been previously treated, patients having already received antibiotics with persistent or recurrent infections showed more of a tendency toward mixed infections. Anaerobic, mycobacterial, and fungal infections were also increased. Antibiotic susceptibility studies showed the cephalosporins and clindamycin maintain a reasonably good coverage (78% and 72%, respectively). Penicillinase-resistant antibiotics also provided some coverage in two thirds of patients. Proper antibiotic therapy may depend on several factors including previous treatment. Other measures of surgical drainage when appropriate, elevation, compresses, and splinting remain important.
我们研究了132例手部感染患者的病例资料、细菌培养及药敏数据，这些数据来自5年的临床经验。患者被分为未接受过先前治疗的患者和先前接受过抗生素治疗的患者。病例资料显示，大多数患者为中青年男性。体温、脉搏和白细胞计数通常仅轻度升高，通常不具有诊断意义。与未接受过先前治疗的患者相比，已经接受过抗生素治疗但仍有持续性或复发性感染的患者更倾向于混合感染。厌氧菌、分枝杆菌和真菌感染也有所增加。抗生素敏感性研究表明，头孢菌素和克林霉素保持了较好的覆盖范围（分别为78%和72%）。耐青霉素酶的抗生素在三分之二的患者中也提供了一定的覆盖。适当的抗生素治疗可能取决于几个因素，包括先前的治疗情况。其他适当的外科引流措施、抬高、冷敷和夹板固定仍然很重要。
