Owusu-Sarpong Obed Jones, Abass Kabila, Buor Daniel, Tutu Solomon Osei, Gyasi Razak M
Department of Geography and Rural Development, Kwame Nkrumah University of Science and Technology, Kumasi, Ghana.
Department of Social Science, Offinso College of Education, Offinso, Ashanti Region, Ghana.
PLoS One. 2024 Dec 31;19(12):e0312312. doi: 10.1371/journal.pone.0312312. eCollection 2024.
Data on the association between sleep problems and chronic conditions among single parents in low- and middle-income countries (LMICs) are limited, and no study has, to date, reported the serial mediation effects of functional limitations and poor health-related quality of life (HRQoL) in this association. This study examines the extent to which functional limitations and poor HRQoL serially explain the link between sleep problems and chronic conditions among single parents in Ghana.
Data on 627 single mothers and fathers were obtained through a multi-stage stratified sampling technique. Sleep duration, nocturnal sleep problems, and daytime sleep problems were used to assess sleep problems. The EQ-5D-3L questionnaire was used to measure HRQoL. Multivariable OLS models and bootstrapping serial mediation analyses were performed to evaluate the hypothesized associations.
The mean age (SD) was 45.0 (14.66) years; 67.3% females. After full adjustment, sleep problems were significantly associated with increases in chronic conditions (β = .238, 95%CI = .100-.377), poor HRQoL (β = .604, 95%CI = .450-.757), and functional limitations (β = .234, 95%CI = .159-.307). Chronic conditions were positively influenced by poor HRQoL (β = .352, 95%CI = .284-.421) and functional limitations (β = .272, 95%CI = .112-.433). Sleep problems were indirectly related to chronic conditions via poor HRQoL (β = .213, BootSE = .039, 95%CI = .143-.295), functional limitations (β = .063, BootSE = .029, 95%CI = .013-.130) and functional limitations → HRQoL (β = .099, BootSE = .025, 95%CI = .054-.152), mediating 34.70%, 10.31% and 16.15% of the total effect, respectively.
Sleep problems and poor HRQoL were positively associated with chronic conditions. Functional limitations and poor HRQoL partially and serially explained this association. Efforts to address chronic conditions among single parents should consider interventions for sleep problems and physiological health outcomes, particularly in LMICs.
关于低收入和中等收入国家(LMICs)单亲家庭中睡眠问题与慢性病之间关联的数据有限,且迄今为止尚无研究报告功能受限和健康相关生活质量(HRQoL)差在这种关联中的系列中介作用。本研究考察了功能受限和HRQoL差在多大程度上系列解释了加纳单亲家庭中睡眠问题与慢性病之间的联系。
通过多阶段分层抽样技术获取了627名单亲母亲和父亲的数据。使用睡眠时间、夜间睡眠问题和日间睡眠问题来评估睡眠问题。使用EQ-5D-3L问卷来测量HRQoL。进行多变量OLS模型和自抽样系列中介分析以评估假设的关联。
平均年龄(标准差)为45.0(14.66)岁;女性占67.3%。经过全面调整后,睡眠问题与慢性病增加(β = 0.238,95%置信区间 = 0.100 - 0.377)、HRQoL差(β = 0.604,95%置信区间 = 0.450 - 0.757)和功能受限(β = 0.234,95%置信区间 = 0.159 - 0.307)显著相关。慢性病受到HRQoL差(β = 0.352,95%置信区间 = 0.284 - 0.421)和功能受限(β = 0.272,95%置信区间 = 0.112 - 0.433)的正向影响。睡眠问题通过HRQoL差(β = 0.213,自抽样标准误 = 0.039,95%置信区间 = 0.143 - 0.295)、功能受限(β = 0.063,自抽样标准误 = 0.029,95%置信区间 = 0.013 - 0.130)以及功能受限→HRQoL(β = 0.099,自抽样标准误 = 0.025,95%置信区间 = 0.054 - 0.152)与慢性病间接相关,分别介导了总效应的34.70%、10.31%和16.15%。
睡眠问题和HRQoL差与慢性病呈正相关。功能受限和HRQoL差部分且系列地解释了这种关联。解决单亲家庭慢性病问题的努力应考虑针对睡眠问题和生理健康结果的干预措施,特别是在低收入和中等收入国家。