Programming the heart: prenatal glucocorticoids and sex-specific cardiovascular risk.
作者信息
Caldwell Jessica L
机构信息
Department of Pharmacology, UC Davis Health System, Davis, California, United States.
出版信息
Am J Physiol Heart Circ Physiol. 2025 Feb 1;328(2):H245-H246. doi: 10.1152/ajpheart.00884.2024. Epub 2024 Dec 31.
Abstract
摘要
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本文引用的文献
1
Prenatal dexamethasone programs autonomic dysregulation in female rats.产前地塞米松会导致雌性大鼠出现自主神经调节异常。
Am J Physiol Heart Circ Physiol. 2025 Feb 1;328(2):H209-H220. doi: 10.1152/ajpheart.00075.2024. Epub 2024 Dec 24.
2
Prenatal glucocorticoids exposure and adverse cardiovascular effects in offspring.产前糖皮质激素暴露与后代不良心血管效应。
Front Endocrinol (Lausanne). 2024 Sep 16;15:1430334. doi: 10.3389/fendo.2024.1430334. eCollection 2024.
3
The molecular mechanisms in prenatal drug exposure-induced fetal programmed adult cardiovascular disease.产前药物暴露诱导胎儿成年期心血管疾病的分子机制。
Front Pharmacol. 2023 Apr 20;14:1164487. doi: 10.3389/fphar.2023.1164487. eCollection 2023.
4
Impact of angiotensin II receptor antagonism on the sex-selective dysregulation of cardiovascular function induced by in utero dexamethasone exposure.血管紧张素 II 受体拮抗作用对宫内地塞米松暴露致心血管功能性别选择性失调的影响。
Am J Physiol Heart Circ Physiol. 2022 Apr 1;322(4):H597-H606. doi: 10.1152/ajpheart.00587.2021. Epub 2022 Feb 18.
5
Prenatal glucocorticoid exposure programs adrenal PNMT expression and adult hypertension.产前糖皮质激素暴露会影响肾上腺苯乙醇胺N-甲基转移酶（PNMT）的表达及成年期高血压。
J Endocrinol. 2015 Nov;227(2):117-27. doi: 10.1530/JOE-15-0244.
6
Glucocorticoids, prenatal stress and the programming of disease.糖皮质激素、产前应激与疾病的发生发展。
Horm Behav. 2011 Mar;59(3):279-89. doi: 10.1016/j.yhbeh.2010.06.007. Epub 2010 Jun 19.
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The relationship of autonomic imbalance, heart rate variability and cardiovascular disease risk factors.自主神经失衡、心率变异性与心血管疾病危险因素的关系。
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Prenatal dexamethasone 'programmes' hypotension, but stress-induced hypertension in adult offspring.产前地塞米松会“引发”成年后代的低血压，但会导致应激性高血压。
J Endocrinol. 2008 Feb;196(2):343-52. doi: 10.1677/JOE-07-0327.
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Glucocorticoids and the development of neuronal function: effects of prenatal dexamethasone exposure on central noradrenergic activity.糖皮质激素与神经元功能的发育：产前暴露于地塞米松对中枢去甲肾上腺素能活性的影响。
Biol Neonate. 1992;61(5):326-36. doi: 10.1159/000243761.
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Promotional role for glucocorticoids in the development of intracellular signalling: enhanced cardiac and renal adenylate cyclase reactivity to beta-adrenergic and non-adrenergic stimuli after low-dose fetal dexamethasone exposure.糖皮质激素在细胞内信号传导发育中的促进作用：低剂量胎儿地塞米松暴露后心脏和肾脏腺苷酸环化酶对β-肾上腺素能和非肾上腺素能刺激的反应性增强。
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