Wang Rui, Wang Jingyuan, Wang Zhichao, Pan Jiaojiao, Sun Shiru, Ma Cuixia, Tang Xiaobing, Lv Shaoqi, Zhai Sicheng, Zhao Ge
School of Medical Engineering, Haojing College of Shaanxi University of Science & Technology, Xi'an 712046, Shaanxi, PR China.
Key Laboratory of Basic and New Drug Research in Chinese Medicine, College of Pharmacy, Shaanxi University of Chinese Medicine, Xi'an 712046, Shaanxi, PR China.
Int J Biol Macromol. 2025 Mar;293:139316. doi: 10.1016/j.ijbiomac.2024.139316. Epub 2024 Dec 29.
Gracilaria/Gracilariopsis lemaneiformis is an ecologically and economically valuable seaweed that has attracted attention for its unique flavour and rich nutritional content. Studies have shown that G. lemaneiformis contains a variety of chemical components, among which G. lemaneiformis polysaccharides (GLPs) are the main active components. GLPs are a class of biomolecules with significant pharmacological activities, which exhibit a variety of bioactivities in vitro and in vivo, including anti-inflammatory, immunomodulatory, regulating lipid metabolism, anti-oxidant, anti-allergic, and anti-cancer activity. Despite the great potential value of GLPs, their current research and review are still relatively limited, which hinders their development and utilization to some extent. Therefore, this study aims to systematically summaries the latest information on GLPs, covering extraction and purification methods, structural characterization, biological activities and conformational relationships. In addition, the potential applications of GLPs and related bibliometrics will be analyzed to provide basic data and references for future studies. In conclusion, this study will contribute to an in-depth understanding of the properties of GLPs and provide a strong scientific basis and direct reference for their more scientific and rational applications.
龙须菜是一种具有生态和经济价值的海藻,因其独特的风味和丰富的营养成分而备受关注。研究表明,龙须菜含有多种化学成分,其中龙须菜多糖(GLPs)是主要的活性成分。GLPs是一类具有显著药理活性的生物分子,在体外和体内均表现出多种生物活性,包括抗炎、免疫调节、调节脂质代谢、抗氧化、抗过敏和抗癌活性。尽管GLPs具有巨大的潜在价值,但其目前的研究和综述仍然相对有限,这在一定程度上阻碍了它们的开发和利用。因此,本研究旨在系统总结GLPs的最新信息,涵盖提取和纯化方法、结构表征、生物活性和构象关系。此外,还将分析GLPs的潜在应用和相关文献计量学,为未来的研究提供基础数据和参考。总之,本研究将有助于深入了解GLPs的特性,并为其更科学合理的应用提供有力的科学依据和直接参考。